Venue - Targeted Protein Degradation Summit
Whilst continuing to deliver breaking clinical updates first and foremost from the field’s key players; Nurix Therapeutics, C4 Therapeutics, Foghorn Therapeutics, Arvinas, and Kymera Therapeutics, the summit also featured an additional discovery track, to cater for and support the rapidly expanding network of early-stage developers in the field.
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Targeted Protein Degradation Summit 2019 - Development of Novel Therapeutics via Stabilization of 14-3-3: Client Protein Protein Interactions
Regulating the activity of phosphorylated client proteins, many of which are “undruggable”, through 14-3-3, a ubiquitously expressed hub protein Binding exclusively to disordered regions of these clients creating an ordered binary complex which can be targeted by small molecule stabilizers Developing small molecule therapeutics that bind the composite 14-3-3:client protein surface to drug the undruggableRead more
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Targeted Protein Degradation Summit 2019 - Panel Discussion: Developing TPD Study Design for Preclinical Safety Assessment of Degraders
• Are current guidelines for assessing the safety of small-molecule therapeutics adequate – are there TPD specific risks? • What is the current decision-making framework for assessing TPD safety risks, e.g. how to assess off-target degradation risks in vitro, and how to select preclinical safety species? • Should safety assessment of PROTACs and Molecular Glues…Read more
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Targeted Protein Degradation Summit 2019 - Oerth Bio’s Attune™ Platform: Delivering on the Promise of TPD in Agriculture
Realizing the promise of TPD in agriculture for crop protection and crop efficiency Showcasing the Oerth Bio’s Attune™ platform to unlock potency, selectivity, and tunability of TPD in agriculture Disclosing exciting recent results from the fieldRead more
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The company 16505 - 3rd Targeted Protein Degradation Summit is located in London, England, United Kingdom. It's worth noting that the company may has more corporate locations
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