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Dream Leaf
Ogden, United States
- Employees
-
We are seeking to expand human consciousness through the medium of dreams. We are dedicated to implementing the latest lucid dreaming research, especially with respect to human neurology. Our company's mission statement can be summed up by one word: consciousness. We feel confident that nutritional supplements offer the most powerful method for conscious dreaming. Alternatively use it as a simple call to action with a link to a product or a page. The biggest reason we become unconscious while we dream is because there is a special neurotransmitter called acetylcholine that begins to break down in the brain as soon our heads hit the pillow.
Product
Galantamine - 6 mg - Acetylcholinesterase Inhibitor
TruDiagno
Navi Mumbai, India
11-50 Employees
2021
Our vision is to offer cutting-edge diagnostics and weave patient-friendly experiences around it that are built on trust, compassion and reliability. We are well equipped with automated equipment like Real-time PCR, and DNA/RNA extraction systems. We provide the highest quality molecular laboratory testing to be relied upon by the clinicians for their patients. TruDiagno core employees comprise a team of well trained phlebotomist, logistic, experienced medical technologists & pathologists who are proactive and take utmost care of your sample & report. TruDiagno is transparent and communication is clear and direct. We provide customised wellness plans as per your team’s unique needs. We are a ISO 9001 & 15189 certified lab. Incorporated as Chromosome Labs Private Limited, TruDiagno is a fast-growing, innovation-driven diagnostics startup based in Mumbai with state-of-the-art laboratory facilities.
Core business
Acetylcholinesterase - OPC Poisoning
Xcess Biosciences Inc.
San Diego, United States
1-10 Employees
2012
Xcess Biosciences Inc (XcessBio or Xbio) was founded in 2008 by scientists from academia and BioPharma industry with strong expertise in chemistry and biology. We are dedicated to develop high-quality products and deliver the best services for our customers. We diligently develop high quality products and strive to earn your satisfaction. If you know of any technology, product, or service development opportunities in the fields related, we would be very interested in hearing from you. SD70 is a potent, selective and cell-permeable inhibitor of histone demethylase JMJD2 (KDM4C), identified by phenotypic screening for inhibitors of ligand and genotoxic stress-induced translocations in prostate cancer cells.
Product
Edrophonium chloride – Xcess Biosciences
3D Molecular Designs
Milwaukee, United States
11-50 Employees
1999
Throughout the year, we offer interactive modeling sessions through regional and national conferences. Click here to learn more about our sessions at upcoming conferences. We love that teachers are lifelong learners! We offer a variety of opportunities to connect with complex content and engaging pedagogy all year long. For answers to questions about ordering, shipping, product details, and more, please explore our help center. Be the first to hear about our latest news, products, and resources conveniently delivered to your inbox!
Product
Neurotransmitters, Synapses & Acetylcholinesterase Webinar
Rosemont Pharmaceuticals
Leeds, United Kingdom
101-250 Employees
1967
We manufacture and supply medicines to support patients with dysphagia and swallowing difficulties. Our mission is to be a rapid developer, a reliable manufacturer and a global supplier of novel-delivery, patient-focused medicines. We are the go-to speciality pharma company if you need a liquid format. Rosemont has over 50 years of experience delivering oral liquid medicines for patients with swallowing difficulties, across a range of therapeutic areas. As a trusted name in liquid medicine, Rosemont supplies solutions to over 27 international markets. When you partner with Rosemont, you’ll gain access to our wide expertise in liquid medications, a continuously growing portfolio, as well as the latest technology in research, development and manufacturing. We’re continually evolving our product range to align with the latest technologies. Our very own innovation centre is our hub for innovating new products directly from our manufacturing site in Leeds.
Product
Donepezil Hydrochloride Oral Solution - Acetylcholinesterase Inhibitor - Rosemont Pharmaceuticals
Genebio
-
- Employees
-
We are happy to announce that we are an official supplier for the Canadian Government. We are passionate about providing customers with outstanding value for money. With upto 75% OFF on products, we want to help you save big this year! GeneBio Systems is a team of specialists dedicated to providing high-performance, and cost-effective products. We strive to serve the scientific community by offering laboratory products for both clinical and academic research. Supporting some of the most research-intensive institutions in Canada, we are committed to fufilling laboratory needs in all aspects of Molecular and Cellular Biology. Established in 2011 in Toronto Ontario, GeneBio Systems is a small yet rapidly growing company in the biotechnology industry. GeneBio Systems prides itself on the value, quality, and customer service it provides through its products and services.
Product
Recombinant Bovine Acetylcholinesterase(ACHE)
Chemodex AG
St. Gallen, Switzerland
1-10 Employees
2001
Chemodex is specialized in the synthesis of fluorescent substances. We are specialized in the synthesis of fluorescent substances. We provide a diverse product portfolio with over 800 products for your unique needs. Most of our products are delivered in standard packaging, from milligram to gram units or in bulk. We offer a wide range of Fluorescent Detection products and other fine chemicals. The listed products are in stock at any given time. Based on our customer’s needs, we also offer custom packaging and shipment.
Product
Aldicarb - CAS-Number 116-06-3 - Order from Chemodex
Neuro-Bio
Vale of White Horse, United Kingdom
11-50 Employees
2013
Neuro-Bio is a privately owned biotech out of Oxford University with a therapeutic focus on neurodegenerative disease. Neuro-Bio can also measure t14 in blood and is developing this biomarker as a companion diagnostic. This new distinct mechanism is being exploited by Neuro-Bio to develop exciting new drugs to treat Alzheimer’s disease. Join our mailing list to receive the latest news and updates from Neuro-Bio.
Core business
Neuro-Bio's Research Of AChE Present In Neuronal & Non-Neuronal Cells
Jane Thurnell Read
Penzance, United Kingdom
1-10 Employees
-
Product
Muscle Testing Vial of Acetylcholinesterase – Ergopathics
BMC Complementary and Alternative
Budapest, Hungary
1-10 Employees
-
We are committed to providing objective evidence for the efficacy or utilisation of complementary medicine and therapies. BMC Complementary Medicine and Therapies welcomes submissions covering the following broad areas of research. BMC Complementary Medicine and Therapies is committed to evidence-based research. We believe that Complementary and Alternative Medicine (CAM) research should be held to the same standards and evidence threshold as those of medicine research. We welcome manuscripts for submission which meet the following research standards:. Submission of a manuscript to a BMC journal implies that materials described in the manuscript, including all relevant raw data, will be freely available to any scientist wishing to use them for non-commercial purposes. Replication studies BMC Complementary Medicine and Therapies​​​​​​​ welcomes submission of replication studies that provide new insights into previously published results and will evaluate these submissions with the same editorial standards we apply to other submissions. Additional information is available through the journal’s submission guidelines.
Core business
Thwaites leaves and evaluation of its acetylcholinesterase inhibitory activity
Technologies which have been searched by others and may be interesting for you:
Some interesting numbers and facts about your company results for Acetylcholinesterase
Country with most fitting companies | United States |
Amount of fitting manufacturers | 1124 |
Amount of suitable service providers | 1147 |
Average amount of employees | 11-50 |
Oldest suiting company | 1995 |
Youngest suiting company | 2020 |
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Acetylcholinesterase is a critical enzyme responsible for breaking down the neurotransmitter acetylcholine in the synaptic cleft, thus terminating synaptic transmission. This process is essential for the proper functioning of the nervous system, ensuring that nerve signals are correctly switched off after they have been transmitted. Located primarily at neuromuscular junctions and in chemical synapses of the cholinergic type, acetylcholinesterase plays a pivotal role in muscle contraction and the regulation of the activation and deactivation cycles of neurons. Its action allows for the rapid cessation of signal transmission, preventing the accumulation of acetylcholine and continuous stimulation of muscles or neurons, which could lead to various neuromuscular disorders. The importance of acetylcholinesterase extends into medical and pharmacological fields, where inhibitors of the enzyme are used in the treatment of conditions such as myasthenia gravis, a disorder characterized by weakening of the muscles, and Alzheimer's disease, where enhancing cholinergic transmission through the inhibition of acetylcholinesterase has shown therapeutic benefits. Moreover, certain pesticides and nerve agents act by inhibiting acetylcholinesterase, leading to an accumulation of acetylcholine and subsequent overstimulation of the nervous system, showcasing the enzyme's significance in toxicology and its broad impact across various scientific disciplines.
1. Enhanced Neuroprotection
Acetylcholinesterase plays a pivotal role in neuroprotection by breaking down acetylcholine in the synaptic cleft, thereby preventing overstimulation of neurons. This action helps in maintaining neuronal health and function, offering an advantage over alternatives that may not directly contribute to neuroprotective mechanisms.
2. Improved Cognitive Function
By regulating the levels of acetylcholine, a crucial neurotransmitter for learning and memory, acetylcholinesterase indirectly supports cognitive functions. This is particularly beneficial compared to other enzymes or drugs that lack this specific regulatory function, making acetylcholinesterase a preferred option for cognitive enhancement strategies.
3. Therapeutic Applications
Acetylcholinesterase inhibitors are used in the treatment of various neurological disorders, such as Alzheimer's disease, due to their ability to increase acetylcholine concentration in the brain. This therapeutic application provides a significant advantage over alternative treatments that might not directly target the cholinergic system, offering a more focused approach to managing neurodegenerative conditions.
1. Purity Levels
Ensure the supplier can provide Acetylcholinesterase with high purity levels, as this significantly impacts the reliability and accuracy of biochemical assays.
2. Source and Origin
Verify the biological source and origin of Acetylcholinesterase, since the enzyme's activity can vary significantly between species and extraction methods.
3. Stability and Storage Conditions
Consider the stability and recommended storage conditions of the enzyme to ensure it retains its activity over time, which is crucial for long-term experiments.
4. Activity Units per Milligram
Check the specific activity (units/mg) provided by the supplier, as this indicates the enzyme's efficiency and effectiveness in catalyzing reactions.
5. Bulk Availability
Assess if the supplier can meet your bulk requirements without compromising on quality, especially for large-scale industrial or research applications.
6. Regulatory Compliance
Confirm that the supplier adheres to regulatory standards and quality control measures applicable in your region or industry to avoid legal and safety issues.
7. Cost-effectiveness
Evaluate the pricing in relation to the quality and quantity offered to ensure it fits within your budget while meeting your technical requirements.
Acetylcholinesterase, an enzyme critical in breaking down neurotransmitters, finds extensive application across multiple industries, particularly in the development of pharmaceuticals and pesticides. In the pharmaceutical sector, companies leverage acetylcholinesterase inhibitors to fabricate treatments for diseases like Alzheimer's and myasthenia gravis. These inhibitors help increase neurotransmitter levels in the brain, improving communication between nerve cells, thereby alleviating symptoms of these neurodegenerative conditions. In the agricultural industry, acetylcholinesterase's role is pivotal in creating effective pesticides. Chemicals designed to inhibit this enzyme can disrupt the nervous system of pests, leading to their eradication. This application not only helps in safeguarding crops but also ensures higher yield, which is crucial for the global food supply chain. Furthermore, the enzyme finds utility in the development of diagnostic tests for various diseases and exposure to toxic compounds. By measuring acetylcholinesterase activity, healthcare providers can diagnose conditions or ascertain exposure levels to certain chemicals, aiding in timely and appropriate treatment. Each of these use cases underscores the enzyme's versatility and its significance across different sectors. By harnessing acetylcholinesterase's properties, businesses can innovate and enhance their offerings, contributing to advancements in healthcare, agriculture, and beyond.
Acetylcholinesterase, a crucial enzyme in the breakdown of the neurotransmitter acetylcholine, currently sits at an advanced stage in the Technology Readiness Level (TRL) spectrum, primarily due to its well-established understanding and application in both medical and military sectors. This status is attributed to extensive research and development that has propelled its use beyond theoretical exploration into practical applications, such as the development of antidotes for nerve agents and the treatment of conditions like myasthenia gravis. The enzyme's role in terminating neurotransmission at cholinergic synapses by catalyzing the hydrolysis of acetylcholine into choline and acetate has been thoroughly studied, leading to the synthesis of acetylcholinesterase inhibitors. These inhibitors have significant therapeutic value, showcasing the enzyme's direct application in pharmacology. Furthermore, the optimization of these inhibitors, through ongoing clinical trials and refinement of delivery mechanisms, underscores a high level of technical maturity and reliability. The specificity and efficiency of acetylcholinesterase in hydrolyzing acetylcholine, coupled with the ability to engineer inhibitors with precise action modes, illustrate why this enzyme commands a high TRL. The accumulation of empirical evidence supporting its efficacy and safety in various applications further cements its position at this level.
In the short-term, advancements in acetylcholinesterase technology are primarily focused on improving diagnostic methods for detecting nerve agent exposure and certain diseases, such as Alzheimer's. Researchers are developing highly sensitive biosensors that use acetylcholinesterase as a biomarker to quickly and accurately identify these conditions in patients. This technology promises to enhance early diagnosis, enabling more effective intervention strategies. Looking at the mid-term developments, the focus shifts towards therapeutic applications. Innovations are expected in the design of acetylcholinesterase inhibitors, which play a crucial role in managing conditions like Alzheimer's disease and myasthenia gravis. New inhibitors are being designed to be more selective and efficient, reducing side effects and improving patient outcomes. Additionally, there's significant research into using acetylcholinesterase inhibitors as potential treatments for pesticide poisoning, aiming to provide more effective antidotes. In the long-term, the horizon broadens to include the integration of acetylcholinesterase technology within neural interface systems. These systems aim to restore cognitive functions and memory in patients with neurological damage or degenerative diseases. By manipulating acetylcholinesterase activity at the synaptic level, these advanced neural interfaces could offer unprecedented precision in treating cognitive impairments, ushering in a new era of neurotherapeutic interventions.
Some interesting questions that has been asked about the results you have just received for Acetylcholinesterase
What are related technologies to Acetylcholinesterase?
Based on our calculations related technologies to Acetylcholinesterase are Aromatics, Desiccants, Refrigerants, Resins, Green Chemistry
Who are Start-Ups in the field of Acetylcholinesterase?
Start-Ups who are working in Acetylcholinesterase are
Acucare
Which industries are mostly working on Acetylcholinesterase?
The most represented industries which are working in Acetylcholinesterase are Other, IT, Software and Services, Biotechnology, Pharmaceuticals, Healthcare
How does ensun find these Acetylcholinesterase Companies?
ensun uses an advanced search and ranking system capable of sifting through millions of companies and hundreds of millions of products and services to identify suitable matches. This is achieved by leveraging cutting-edge technologies, including Artificial Intelligence.