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Fagus Antibody Services
Oxford, United Kingdom
A
1-10 Employees
2022
Key takeaway
Fagus Antibody Services offers a range of products, including an Acetylcholinesterase (AChE) Rabbit polyclonal antibody. AChE plays a crucial role in hydrolyzing acetylcholine at neuromuscular junctions and cholinergic synapses, thereby terminating signal transmission.
Reference
Product
AChE Rabbit pAb - Fagus Antibody Services
Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of
OYC Europe
Rotterdam, Netherlands
A
1-10 Employees
2007
Key takeaway
OYC Europe specializes in manufacturing biochemical products for the clinical diagnostic industry, including a Choline Esterase pack. With a strong history in coenzyme production and a state-of-the-art facility, OYC Europe is a key supplier of critical raw materials for various markets.
Reference
Product
Choline Esterase pack – OYC EU | Your reliable partner in Biochemical Raw Material and Life Science Service
Genebio
-
- Employees
-
Key takeaway
GeneBio Systems offers Recombinant Bovine Acetylcholinesterase (ACHE), a product relevant for research in Molecular and Cellular Biology. Their commitment to providing high-performance laboratory products supports both clinical and academic research needs.
Reference
Product
Recombinant Bovine Acetylcholinesterase(ACHE) – GeneBio Systems
Recombinant Bovine Acetylcholinesterase(ACHE)
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Xcess Biosciences Inc.
San Diego, United States
B
1-10 Employees
2012
Key takeaway
Xcess Biosciences Inc. offers edrophonium chloride, a reversible acetylcholinesterase inhibitor that prevents the breakdown of acetylcholine, primarily at the neuromuscular junction. This compound is significant in various research and therapeutic contexts related to neurotransmission.
Reference
Product
Edrophonium chloride – Xcess Biosciences
Edrophonium chloride is a readily reversible acetylcholinesterase inhibitor; prevents breakdown of the neurotransmitter acetylcholine and acts by competitively inhibiting the enzyme acetylcholinesterase, mainly at the neuromuscular junction. CAS: 116-38-1. N-ethyl-3-hydroxy-N,N-dimethylanilinium chloride.
Cell Technology
Hayward, United States
B
11-50 Employees
1998
Key takeaway
Cell Technology offers a non-radioactive enzyme activity assay called aCella - AChE, specifically designed for acetylcholinesterase detection. This versatile assay can be used for applications such as nerve gas and pesticide monitoring, as well as drug screening, providing fast and highly sensitive results.
Reference
Product
aCella - AChE by Cell Technology
Safe – Non Radioactive Enzyme activity assay. Versatile: Nerve Gas, Pesticide Monitoring, drug screening Applications Homogenous – One-step, no wash assay. FAST – Results in 30 secs – 5 minutes. Highly Sensitive HTS – Adaptable for High Throughput format
Athens Research & Technology
Athens, United States
B
11-50 Employees
1986
Key takeaway
Athens Research & Technology manufactures highly pure and active human proteins, including butyrylcholinesterase from human plasma, which may be relevant for studies related to Alzheimer's Disease and other conditions.
Reference
Product
Butyrylcholinesterase, Human Plasma | Athens Research & Technology
Neuro-Bio
Vale of White Horse, United Kingdom
A
11-50 Employees
2013
Key takeaway
Neuro-Bio, a biotech company focused on neurodegenerative diseases, is actively researching Acetylcholinesterase (AChE) and its properties in both neuronal and non-neuronal cells. This research supports their development of innovative drugs aimed at treating Alzheimer's disease.
Reference
Core business
Neuro-Bio's Research Of AChE Present In Neuronal & Non-Neuronal Cells
Neuro-Bio development comes from the research & discovery of the properties and behavioural actions of Acetylcholinesterase (AChE).
Asceneuron SA
Lausanne, Switzerland
A
1-10 Employees
2012
Key takeaway
Asceneuron is focused on developing innovative therapeutics for neurodegenerative diseases, specifically targeting toxic protein aggregates associated with conditions like Alzheimer’s and Parkinson’s diseases.
Reference
Core business
Asceneuron
DIAsource ImmunoAssays® S.A.
Ottignies-Louvain-la-Neuve, Belgium
A
51-100 Employees
1996
Key takeaway
DiaSource Diagnostics offers a comprehensive range of RIA and ELISA products, including a specific assay for acetylcholine receptors, which utilizes 125I-alpha-bungarotoxin to label the receptors, ensuring high specificity. This expertise in clinical diagnostics highlights their commitment to quality and customer support in the field of endocrinology and autoimmunity.
Reference
Product
Acetylcholine Receptor, RIA, 100 tests | DiaSource Diagnostics
Acetylcholine receptor from human muscle is used as antigen in this radio receptor assay. The receptors are labelled with 125I-alpha-bungarotoxin. This snake venom binds the receptors most specifically and almost irreversible. Autoantibodies...
EPCA
Brussels, Belgium
A
1-10 Employees
1967
Key takeaway
The company, EPCA, serves as a platform for sharing ideas and knowledge among key industry players, focusing on sustainability and environmental challenges.
Reference
Core business
Aceto | EPCA
Technologies which have been searched by others and may be interesting for you:
Acetylcholinesterase is an enzyme that plays a critical role in the nervous system by breaking down the neurotransmitter acetylcholine. This process is essential for the proper functioning of synapses, as it ensures that the signal between nerve cells is terminated efficiently. By hydrolyzing acetylcholine into acetate and choline, acetylcholinesterase helps prevent continuous stimulation of muscles and nerves, which could lead to muscle spasms or paralysis. The enzyme is widely studied for its implications in various neurological disorders and is also a target for certain drugs and pesticides, making its providers vital for research and therapeutic applications.
Acetylcholinesterase is an enzyme that plays a crucial role in the nervous system by breaking down the neurotransmitter acetylcholine. Once acetylcholine is released into the synaptic cleft, it binds to receptors on the postsynaptic neuron, facilitating the transmission of nerve impulses. After its action, acetylcholine must be rapidly removed to prevent continuous stimulation of the neuron. Acetylcholinesterase catalyzes the hydrolysis of acetylcholine into acetate and choline, effectively terminating the signal and allowing the neuron to reset for the next impulse. This regulation is essential for proper muscle function and maintaining the overall balance of neurotransmission in the body.
Acetylcholinesterase is a crucial enzyme in the process of neurotransmission, particularly within the cholinergic system. It is responsible for the rapid breakdown of the neurotransmitter acetylcholine in the synaptic cleft, which is essential for terminating synaptic transmission. By hydrolyzing acetylcholine into acetate and choline, acetylcholinesterase ensures that neurotransmitter signaling is tightly regulated, preventing continuous stimulation of post-synaptic receptors. This rapid degradation is vital for muscle relaxation and overall neural function, facilitating precise communication between neurons and muscle fibers.
Inhibitors of acetylcholinesterase are primarily utilized in the treatment of various neurological disorders. These compounds work by blocking the enzyme acetylcholinesterase, which is responsible for breaking down the neurotransmitter acetylcholine. As a result, they increase the availability of acetylcholine in the synaptic cleft, enhancing cholinergic transmission. Such inhibitors are particularly effective in managing conditions like Alzheimer's disease, where they help improve cognitive function and memory by facilitating better communication between neurons. Additionally, these inhibitors are used in the treatment of myasthenia gravis, a condition characterized by muscle weakness due to insufficient acetylcholine action at the neuromuscular junction.
Acetylcholinesterase plays a crucial role in muscle contraction by regulating the levels of acetylcholine, a neurotransmitter essential for muscle activation. When a nerve impulse reaches the neuromuscular junction, acetylcholine is released, binding to receptors on the muscle cell membrane, leading to muscle contraction. After this process, acetylcholinesterase rapidly breaks down acetylcholine into acetate and choline, terminating its action. This breakdown is vital as it prevents continuous stimulation of the muscle, allowing it to relax after contraction. Without proper functioning of acetylcholinesterase, acetylcholine could accumulate, resulting in prolonged muscle contraction or spasms, which can hinder normal muscle function.
Some interesting numbers and facts about your company results for Acetylcholinesterase
| Country with most fitting companies | United States |
| Amount of fitting manufacturers | 3305 |
| Amount of suitable service providers | 3309 |
| Average amount of employees | 11-50 |
| Oldest suiting company | 1967 |
| Youngest suiting company | 2022 |
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Some interesting questions that has been asked about the results you have just received for Acetylcholinesterase
What are related technologies to Acetylcholinesterase?
Based on our calculations related technologies to Acetylcholinesterase are Aromatics, Desiccants, Refrigerants, Resins, Green Chemistry
Who are Start-Ups in the field of Acetylcholinesterase?
Start-Ups who are working in Acetylcholinesterase are Fagus Antibody Services
Which industries are mostly working on Acetylcholinesterase?
The most represented industries which are working in Acetylcholinesterase are Other, Healthcare, Biotechnology, Pharmaceuticals, IT, Software and Services
How does ensun find these Acetylcholinesterase Companies?
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