An aptamer is a short fragment of DNA or RNA, typically between 15-100 nucleotides in length, that has the ability to bind to specific molecules and proteins in a highly specific and often reversible manner. Aptamers are similar to antibodies in their ability to recognize and bind to specific targets, but they are much smaller and easier to produce in a laboratory setting.

Aptamers are an emerging technology that is poised to become the next evolution in diagnostics and drug discovery. Aptagen was formed in 2004, and operations began two years later in 2006. The company produces state-of-the-art target-recognition elements for diagnostics, therapeutics, and bio-industrial applications .

Aptamir is developing therapies based on the research of Craig Mello and Andrew fire who won the 2006 Nobel Prize for Physiology or Medicine for the discovery of RNA interference. AptamiR’s distinctive model of virtual, outsourced, and cost-effective drug research and development has resulted in several proof of concept milestones within a few years in operations .

Aptamir is developing therapies based on the research of Craig Mello and Andrew fire who won the 2006 Nobel Prize for Physiology or Medicine for the discovery of RNA interference. Current medical treatments of obesity: - have poor benefit-to-risk profiles - fail to reach their long-term goals and - do not meet patients’ expectations .

NeoVentures was founded in 2002 and has since become the world leader in aptamer development and applications. The company was cofounded by Ms. Ximena Vedoya and Dr. Gregory Penner based on their observation of the need to bridge the gap between discovery and commercial application. Gregory grew up in rural western canada on a tree nursery. he decided to enroll in agriculture at University because he was inspired by Dr. Norman Borlaug obtaining a Nobel Peace Prize for

Aptamer Sciences, Inc. 1 Founded in April 2011 by the best aptamer experts in Korea under the banner of bio company.
Based on the globally competitive Aptamer Technology Platform, they are an R & D-based bio venture company that develops innovative therapeutics and diagnostic technologies that are difficult to develop with protein and genome-based biomaterials. Comprehensive range of pressures from technology to effectively discover high-performance aptamers, to improve and optimize the found aptamers for application purposes, and to develop innovative aptamer new drugs and aptamer-based multi-index diagnostic technology. They are building a tamer technology platform.

Base Pair provides custom aptamer development services and catalog aptamers.  Scientists at Base Pair Biotechnologies have been studying aptamers and developing them on a research basis since 2004 and began recently offering these services commercially. With a patent pending multiplexed approach we can develop custom aptamers at unprecedented time and cost.

The Aptamer group of companies focuses on the development of aptamer technologies. We develop nucleic acid aptamers for use in research & development, biomarker discovery, diagnostics or therapeutic developments. Aptamers are short DNA or RNA sequences that offer high-affinity and specificity to virtually all types of targets. They can therefore be thought of as synthetic nucleic acid equivalents of antibodies. Aptamers are versatile, cost effective and offer a complementary or alternative solution to antibodies. We have over 20 years combined expertise in the development of nucleic acid aptamers to peptides, proteins, cells, tissue samples, micro-organisms and small molecules.

The Aptamer Group of companies has cutting edge platforms for the selection of aptamers. These include semi-automated selection platforms which ensure accurate replication of selection conditions to ensure the best quality aptamers result. We can use a wide range of targets: peptide, proteins, whole cells, viruses, small molecules etc. The typical aptamer selection process can be completed in a matter of weeks. Monoclonal antibodies usually take several months to generate.

Our custom service can be focussed on a particular application so that the resultant aptamers are pre-optimized for use with a given detection platform, sample type and assay buffer. 
Aptamers themselves are increasingly being perceived as the state of the art reagent of choice for a wide range of applications including:

Imaging experiments: fluorescence, bright field and phase contrast, IHC, ICC
Quantification: ELISA (or ELONA), homogeneous assays etc.
Rapid diagnostics: Lateral flow devices, biosensors, electrochemical detection, nano-wires 
Binding studies: label free detection, SPR, Biolayer Interferometry
Purification: affinity chromatography 

We also offer an aptamer based assay development service. 

Our solution can be used to identify aptamers for virtually any application and against almost any target in almost any condition. Our applications are more diverse than those for which antibodies have been used. These include therapeutics, in biomarker discover, in drug target discovery, as diagnostics, in biosensors as components of biochemical tests such as Lateral flow devices, enzyme linked oligonucleotide assays (ELONA: the aptamer based equivalent of ELISA), in affinity chromatography and as research reagents.

For more information visit: www.aptamergroup.com

Achiko AG is developing disruptive diagnostic solutions that puts people first. Its lead product is a rapid, reliable covid-19 test with a companion app offering a user-friendly digital health passport. Headquartered in Zurich, Achiko has offices in Jakarta, and Singapore .

Lucerna, Inc. is a biotechnology tool company focused on developing and commercializing the fluorescent aptamer (SpinachTM) technology. The company's founders have demonstrated expertise in RNA biology, fluorescence imaging, high-throughput screening and assay development .

Science at pure biologics is a continual source of novel ideas, solutions, and interesting scientific results. These results are translated into new therapies for patients in greatest need .

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