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Supa Hot Crew
Germany
A
1-10 Employees
2013
Key takeaway
The company, enzyme.bio, offers a high-quality Hexokinase (HK) enzyme with an activity level of ≥400 U/mg, highlighting their commitment to providing reliable enzyme products for labs and biotech firms.
Reference
Product
Glycerol Kinase (GK) Activity ≥150U/mg - enzymes.bio
Selling unit: per 1ku
Genebio
-
- Employees
-
Key takeaway
GeneBio Systems is a dedicated supplier of laboratory products, including Recombinant Human Hexokinase-1 (HK1), essential for research in Molecular and Cellular Biology. Their commitment to high-performance and cost-effective solutions supports both clinical and academic research needs.
Reference
Product
Recombinant Human Hexokinase-1(HK1) – GeneBio Systems
Recombinant Human Hexokinase-1(HK1)
MyBio Ltd
Ireland
A
1-10 Employees
2009
Key takeaway
MyBio offers a recombinant Ketohexokinase protein, which is relevant for research involving hexokinase. This protein, expressed in E. coli and tagged for easy identification, has a molecular weight of 33.8 kDa, and the company provides access to a wide range of high-quality bioscience products.
Reference
Product
Recombinant Ketohexokinase protein – MyBio Ireland
Recombinant Ketohexokinase protein was expressed in E. coli cells as the full length protein (accession number NP_000212.1) with a C-terminal 6×His-Tag. The molecular weight of the protein is 33.8 kDa. For more complete and up-to-date information, please visit the Active Motif website.
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Xcess Biosciences Inc.
San Diego, United States
B
1-10 Employees
2012
Key takeaway
Xcess Biosciences Inc has developed GKA50 quarterhydrate, a potent glucokinase activator that stimulates insulin release and lowers glucose levels in high-fat-fed female rats. This product highlights the company's focus on innovative solutions in the field of glucose metabolism.
Reference
Product
GKA50 quarterhydrate – Xcess Biosciences
GKA50 quarterhydrate is a potent glucokinase activator (EC50=33 nM at 5 mM glucose) and stimulates insulin release from mouse islets of Langerhans. GKA50 quarterhydrate is a glucose-like activator of beta-cell metabolism in rodent and human islets and a Ca2+-dependent modulator of insulin secretion. GKA50 quarterhydrate shows significant glucose lowering in high fat fed female rats.
OYC Europe
Rotterdam, Netherlands
A
1-10 Employees
2007
Key takeaway
OYC Europe, a subsidiary of Oriental Yeast Co., Ltd., specializes in manufacturing biochemical products for the clinical diagnostic industry, highlighting their expertise and established history in this field. They offer critical raw materials, including the Glucose (HK-G6PDH) Pack, which is relevant to hexokinase-related applications.
Reference
Product
Glucose (HK-G6PDH) Pack – OYC EU | Your reliable partner in Biochemical Raw Material and Life Science Service
Huabio
Huron Charter Township, United States
B
101-250 Employees
2007
Key takeaway
The company, HUABIO, offers the Hexokinase II Rabbit Polyclonal Antibody (HA500186), highlighting its commitment to delivering high-performing antibodies.
Reference
Product
Hexokinase II Rabbit Polyclonal Antibody (HA500186) – HUABIO
HUABIO
Bellbrook Labs
Madison, United States
B
11-50 Employees
2007
Key takeaway
Transcreener offers a universal method for detecting enzymatic reactions, such as measuring ADP for kinases, which is relevant for hexokinase activity assays. Their Adenosine Kinase Assay demonstrates this approach, allowing for efficient and accurate measurement of enzyme activity.
Reference
Product
Adenosine Kinase Assay | ADK Activity Assay Application | BellBrook Labs
Mix-and-read biochemical HTS Adenosine Kinase Assay. Measure ADK Enzyme Activity with an FP, FI, or TR-FRET Readout. Services also available.
ERBA DIAGNOSTICS FRANCE
Castelnau-le-Lez, France
A
11-50 Employees
2012
Key takeaway
The company, Erba Group, specializes in the development and manufacture of products for clinical chemistry, which likely includes their GLUCOSE HK product, relevant for glucose analysis. Their mission emphasizes providing high-quality and accessible diagnostic tools that enhance patient treatment efficiency.
Reference
Product
GLUCOSE HK | Klinická biochemie | BIOLATEST | Erba Lachema s.r.o.
Kinase Logistics Europe
Meyn, Germany
A
1-10 Employees
2009
Key takeaway
The company, Carna Biosciences, Inc., specializes in protein kinase products and services, which are crucial for kinase drug development. They offer a range of recombinant human protein and lipid kinases, including those suitable for activity assays and binding studies, as well as assay kits for over 300 human kinase targets.
Reference
Product
Kinases and Substrates | Kinase Logistics Europe: kinaselogistics
Recombinant Human Kinase | Biotinylated Kinases | Inactive Mutant Kinases | Substrates.
Proteros biostructures GmbH
Planegg, Germany
A
51-100 Employees
1998
Key takeaway
The company, Proteros, specializes in early drug discovery research, emphasizing their expertise and commitment to overcoming scientific challenges. They provide structure-based drug discovery services that could be relevant for projects involving hexokinase, particularly in the context of lead optimization and clinical programs.
Reference
Product
GCK (human) (12-465)
GCK (human) was expressed and purified from E.coli. The protein was expressed as a N-terminal HIS-fusion protein and purified by a four-step chromatographic procedure comprising afiinity, ion exchange and size exclusion chromatography steps including tag cleavage.
Technologies which have been searched by others and may be interesting for you:
Hexokinase is an important enzyme that plays a crucial role in glucose metabolism. It catalyzes the phosphorylation of glucose to form glucose-6-phosphate, which is a key step in the glycolytic pathway. This enzyme is found in various tissues throughout the body, including the liver and brain, and exists in several isoforms, each with distinct properties and regulatory mechanisms. Hexokinase functions effectively in a low-glucose environment, ensuring that cells can efficiently utilize glucose for energy production. Its activity is tightly regulated, making it essential for maintaining glucose homeostasis and energy balance in living organisms.
Hexokinase plays a crucial role in glucose metabolism by catalyzing the phosphorylation of glucose to glucose-6-phosphate. This reaction is the first step in the glycolytic pathway, which is essential for energy production in cells. By converting glucose into a form that can be utilized for energy or stored as glycogen, hexokinase ensures that cells have a readily available supply of energy. The enzyme is found in various tissues, particularly in muscle and brain cells, where it helps maintain energy homeostasis. Different isoforms of hexokinase exist, each with distinct regulatory properties and tissue distributions, allowing for precise control of glucose utilization according to the metabolic needs of the organism.
Hexokinase is a crucial enzyme in glucose metabolism, primarily responsible for the phosphorylation of glucose to form glucose-6-phosphate. This reaction is the first step in the glycolytic pathway, which is essential for cellular energy production. By converting glucose into its phosphorylated form, hexokinase effectively traps glucose within the cell, preventing it from freely diffusing back out. Additionally, glucose-6-phosphate serves as a pivotal molecule that can enter various metabolic pathways, including glycolysis, glycogenesis, and the pentose phosphate pathway. This versatility underscores the importance of hexokinase in regulating glucose levels and facilitating energy production in cells.
Hexokinase plays a crucial role in medical research due to its function in glucose metabolism. This enzyme catalyzes the phosphorylation of glucose to glucose-6-phosphate, a fundamental step in glycolysis. Understanding hexokinase activity is essential for studying metabolic disorders, diabetes, and cancer, as altered hexokinase levels can indicate changes in cellular energy metabolism and proliferation. Research into hexokinase also aids in the development of therapeutic strategies. For instance, targeting hexokinase can help in the design of drugs aimed at regulating glucose levels or inhibiting cancer cell growth. Its involvement in various metabolic pathways makes it a significant focus for scientists investigating metabolism-related diseases.
Hexokinase activity can be measured using various biochemical assays that typically involve the phosphorylation of glucose. In a common method, a sample containing hexokinase is mixed with a known concentration of glucose and ATP. The reaction results in the formation of glucose-6-phosphate and ADP. The activity of hexokinase is determined by quantifying the amount of glucose-6-phosphate produced over a specific time frame. This can be achieved using colorimetric assays, where the formation of glucose-6-phosphate is coupled with a secondary reaction that produces a colored product, allowing for spectrophotometric measurement. Additionally, some methods utilize radiolabeled glucose to track the phosphorylation process, providing precise measurements of hexokinase activity.
Some interesting numbers and facts about your company results for Hexokinase
| Country with most fitting companies | United States |
| Amount of fitting manufacturers | 2525 |
| Amount of suitable service providers | 1623 |
| Average amount of employees | 11-50 |
| Oldest suiting company | 1998 |
| Youngest suiting company | 2013 |
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Some interesting questions that has been asked about the results you have just received for Hexokinase
What are related technologies to Hexokinase?
Based on our calculations related technologies to Hexokinase are Aromatics, Desiccants, Refrigerants, Resins, Green Chemistry
Which industries are mostly working on Hexokinase?
The most represented industries which are working in Hexokinase are Biotechnology, Other, Healthcare, Pharmaceuticals, Medical
How does ensun find these Hexokinase Companies?
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