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Top Hexokinase Companies

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60 companies for Hexokinase

Supa Hot Crew's Logo

Supa Hot Crew

Germany

A

1-10 Employees

2013

Key takeaway

The company, enzyme.bio, offers a high-quality Hexokinase (HK) enzyme with an activity level of ≥400 U/mg, highlighting their commitment to providing reliable enzyme products for labs and biotech firms.

Reference

Product

Glycerol Kinase (GK) Activity ≥150U/mg - enzymes.bio

Selling unit: per 1ku

Genebio's Logo

Genebio

-

- Employees

-

Key takeaway

GeneBio Systems is a dedicated supplier of laboratory products, including Recombinant Human Hexokinase-1 (HK1), essential for research in Molecular and Cellular Biology. Their commitment to high-performance and cost-effective solutions supports both clinical and academic research needs.

Reference

Product

Recombinant Human Hexokinase-1(HK1) – GeneBio Systems

Recombinant Human Hexokinase-1(HK1)

OYC Europe's Logo

OYC Europe

Rotterdam, Netherlands

A

1-10 Employees

2007

Key takeaway

OYC Europe, a subsidiary of Oriental Yeast Co., Ltd., specializes in manufacturing biochemical products for the clinical diagnostic industry, highlighting their expertise and established history in this field. They offer critical raw materials, including the Glucose (HK-G6PDH) Pack, which is relevant to hexokinase-related applications.

Reference

Product

Glucose (HK-G6PDH) Pack – OYC EU | Your reliable partner in Biochemical Raw Material and Life Science Service

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Xcess Biosciences Inc.'s Logo

Xcess Biosciences Inc.

San Diego, United States

B

1-10 Employees

2012

Key takeaway

Xcess Biosciences Inc has developed GKA50 quarterhydrate, a potent glucokinase activator that stimulates insulin release and lowers glucose levels in high-fat-fed female rats. This product highlights the company's focus on innovative solutions in the field of glucose metabolism.

Reference

Product

GKA50 quarterhydrate – Xcess Biosciences

GKA50 quarterhydrate is a potent glucokinase activator (EC50=33 nM at 5 mM glucose) and stimulates insulin release from mouse islets of Langerhans. GKA50 quarterhydrate is a glucose-like activator of beta-cell metabolism in rodent and human islets and a Ca2+-dependent modulator of insulin secretion. GKA50 quarterhydrate shows significant glucose lowering in high fat fed female rats.

MyBio Ltd's Logo

MyBio Ltd

Ireland

A

1-10 Employees

2009

Key takeaway

MyBio offers a recombinant Ketohexokinase protein, which is relevant for research involving hexokinase. This protein, expressed in E. coli and tagged for easy identification, has a molecular weight of 33.8 kDa, and the company provides access to a wide range of high-quality bioscience products.

Reference

Product

Recombinant Ketohexokinase protein – MyBio Ireland

Recombinant Ketohexokinase protein was expressed in E. coli cells as the full length protein (accession number NP_000212.1) with a C-terminal 6×His-Tag. The molecular weight of the protein is 33.8 kDa. For more complete and up-to-date information, please visit the Active Motif website.

Huabio's Logo

Huabio

Huron Charter Township, United States

B

101-250 Employees

2007

Key takeaway

The company, HUABIO, offers the Hexokinase II Rabbit Polyclonal Antibody (HA500186), highlighting its commitment to delivering high-performing antibodies.

Reference

Product

Hexokinase II Rabbit Polyclonal Antibody (HA500186) – HUABIO

HUABIO

ERBA DIAGNOSTICS FRANCE's Logo

ERBA DIAGNOSTICS FRANCE

Castelnau-le-Lez, France

A

11-50 Employees

2012

Key takeaway

The company, Erba Group, specializes in the development and manufacture of products for clinical chemistry, which likely includes their GLUCOSE HK product, relevant for glucose analysis. Their mission emphasizes providing high-quality and accessible diagnostic tools that enhance patient treatment efficiency.

Reference

Product

GLUCOSE HK | Klinická biochemie | BIOLATEST | Erba Lachema s.r.o.

Glukos's Logo

Glukos

Gresham, United States

B

1-10 Employees

2009

Key takeaway

Glukos offers a range of energy products, including gels and gummies, that provide quick and sustainable energy through all-natural ingredients. This focus on natural sports nutrition may be relevant for understanding the role of hexokinase in energy metabolism.

Reference

Core business

Glukos Energy Official Website | Glukos Energy

All-natural sports nutrition products, made with simple ingredients. Energy gels, energy gummies and energy drink mix. Quick, sustainable energy to keep you moving. Shop today!

Bellbrook Labs's Logo

Bellbrook Labs

Madison, United States

B

11-50 Employees

2007

Key takeaway

Transcreener offers a universal method for detecting enzymatic reactions, such as measuring ADP for kinases, which is relevant for hexokinase activity assays. Their Adenosine Kinase Assay demonstrates this approach, allowing for efficient and accurate measurement of enzyme activity.

Reference

Product

Adenosine Kinase Assay | ADK Activity Assay Application | BellBrook Labs

Mix-and-read biochemical HTS Adenosine Kinase Assay. Measure ADK Enzyme Activity with an FP, FI, or TR-FRET Readout. Services also available.

Glucolytics's Logo

Glucolytics

Dallas, United States

B

1-10 Employees

2015

Key takeaway

Glucolytics focuses on optimizing data to make it consumable and actionable, which can be essential for informed decision-making.

Reference

Core business

Glucolytics - Sweeten Your Data


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Things to know about Hexokinase

What is Hexokinase?

Hexokinase is an important enzyme that plays a crucial role in glucose metabolism. It catalyzes the phosphorylation of glucose to form glucose-6-phosphate, which is a key step in the glycolytic pathway. This enzyme is found in various tissues throughout the body, including the liver and brain, and exists in several isoforms, each with distinct properties and regulatory mechanisms. Hexokinase functions effectively in a low-glucose environment, ensuring that cells can efficiently utilize glucose for energy production. Its activity is tightly regulated, making it essential for maintaining glucose homeostasis and energy balance in living organisms.


How does Hexokinase function in the body?

Hexokinase plays a crucial role in glucose metabolism by catalyzing the phosphorylation of glucose to glucose-6-phosphate. This reaction is the first step in the glycolytic pathway, which is essential for energy production in cells. By converting glucose into a form that can be utilized for energy or stored as glycogen, hexokinase ensures that cells have a readily available supply of energy. The enzyme is found in various tissues, particularly in muscle and brain cells, where it helps maintain energy homeostasis. Different isoforms of hexokinase exist, each with distinct regulatory properties and tissue distributions, allowing for precise control of glucose utilization according to the metabolic needs of the organism.


What role does Hexokinase play in glucose metabolism?

Hexokinase is a crucial enzyme in glucose metabolism, primarily responsible for the phosphorylation of glucose to form glucose-6-phosphate. This reaction is the first step in the glycolytic pathway, which is essential for cellular energy production. By converting glucose into its phosphorylated form, hexokinase effectively traps glucose within the cell, preventing it from freely diffusing back out. Additionally, glucose-6-phosphate serves as a pivotal molecule that can enter various metabolic pathways, including glycolysis, glycogenesis, and the pentose phosphate pathway. This versatility underscores the importance of hexokinase in regulating glucose levels and facilitating energy production in cells.


Why is Hexokinase important in medical research?

Hexokinase plays a crucial role in medical research due to its function in glucose metabolism. This enzyme catalyzes the phosphorylation of glucose to glucose-6-phosphate, a fundamental step in glycolysis. Understanding hexokinase activity is essential for studying metabolic disorders, diabetes, and cancer, as altered hexokinase levels can indicate changes in cellular energy metabolism and proliferation. Research into hexokinase also aids in the development of therapeutic strategies. For instance, targeting hexokinase can help in the design of drugs aimed at regulating glucose levels or inhibiting cancer cell growth. Its involvement in various metabolic pathways makes it a significant focus for scientists investigating metabolism-related diseases.


How is Hexokinase activity measured?

Hexokinase activity can be measured using various biochemical assays that typically involve the phosphorylation of glucose. In a common method, a sample containing hexokinase is mixed with a known concentration of glucose and ATP. The reaction results in the formation of glucose-6-phosphate and ADP. The activity of hexokinase is determined by quantifying the amount of glucose-6-phosphate produced over a specific time frame. This can be achieved using colorimetric assays, where the formation of glucose-6-phosphate is coupled with a secondary reaction that produces a colored product, allowing for spectrophotometric measurement. Additionally, some methods utilize radiolabeled glucose to track the phosphorylation process, providing precise measurements of hexokinase activity.


Insights about the Hexokinase results above

Some interesting numbers and facts about your company results for Hexokinase

Country with most fitting companiesGermany
Amount of fitting manufacturers1321
Amount of suitable service providers875
Average amount of employees1-10
Oldest suiting company2007
Youngest suiting company2015

Geographic distribution of results





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Frequently asked questions (FAQ) about Hexokinase Companies

Some interesting questions that has been asked about the results you have just received for Hexokinase

Based on our calculations related technologies to Hexokinase are Aromatics, Desiccants, Refrigerants, Resins, Green Chemistry

The most represented industries which are working in Hexokinase are Other, Biotechnology, Healthcare, Pharmaceuticals, Food and Beverage

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