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FLUOROGENICS LIMITED
Salisbury, United Kingdom
A
1-10 Employees
2011
Key takeaway
The company offers a range of products including the NEBNext UltraExpress™ FS DNA Library Prep Kit, which utilizes a single enzyme mix for key processes like end prep and dA-tailing. Additionally, they highlight their expertise in assembly techniques, which may be relevant for those interested in ligation strategies.
Reference
Product
Ligase Quality | NEB
ArcticZymes Technologies ASA
Tromsø, Norway
A
11-50 Employees
1990
Key takeaway
ArcticZymes Technologies specializes in enzymatic solutions, emphasizing their innovative ArcticZymes R2D Ligase™, the first ligase capable of ligating DNA to RNA. Their commitment to high-quality, customized enzymes enhances molecular research and therapeutics.
Reference
Product
ArcticZymes R2D Ligase™ - ArcticZymes Technologies
ArcticZymes R2D LigaseTMnnArcticZymes RNA to DNA Ligase (ArcticZymes R2D LigaseTM) is the first ligase on the market that is able to ligate DNA to
Genebio
-
- Employees
-
Key takeaway
GeneBio Systems offers Recombinant Escherichia coli DNA ligase (ligA), highlighting their commitment to providing high-performance laboratory products for molecular and cellular biology research.
Reference
Product
Recombinant Escherichia coli DNA ligase(ligA) – GeneBio Systems
Recombinant Escherichia coli DNA ligase(ligA)
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Codexis
Temecula, United States
B
51-100 Employees
2002
Key takeaway
Codexis has developed a new engineered ligase, CDX Ligase, which significantly enhances ligation efficiency, library yield, and complexity, addressing key challenges in sequencing. Their focus on innovative enzyme solutions aims to improve the production and quality of mRNA and other biopharmaceuticals.
Reference
Product
CDX Ligase (Pre-commercial) :: Codexis, Inc. (CDXS)
A newly engineered ligase to address sequencing challenges by delivering higher ligation efficiency, library yield and complexity.
Prokazyme.com
Reykjavik, Iceland
A
1-10 Employees
2013
Key takeaway
Prokazyme offers a thermostable DNA ligase derived from Rhodothermus marinus, which operates effectively between 5 and 65°C and ensures high-fidelity ligation of DNA. This enzyme is particularly useful for research and diagnostic applications.
Reference
Product
Rma DNA ligase from Rhodothermus marinus | Prokazyme
DNA ligase from Rhodothermus marinus is a thermostable NAD+ dependent double-stranded DNA ligase with broad temperatures range between 5 and 65°C. The enzyme catalyzes ligation of DNA with high fidelity and is suitable for various ...
Intact Genomics
Creve Coeur, United States
B
1-10 Employees
2013
Key takeaway
Intact Genomics offers T4 DNA Ligase, which boasts 5X the efficiency of NEB, making it a valuable tool for various molecular biology applications. Their commitment to quality and competitive pricing ensures that researchers have access to top-tier ligase products.
Reference
Product
T4 DNA Ligase - Intact Genomics
Intact Genomics T4 DNA Ligase displays 5X the efficiency of NEB, available for a competitive price. Bulk prices available!
Kactus Biosystems
-
11-50 Employees
2018
Key takeaway
KACTUS specializes in high-purity recombinant proteins and enzymes, including T4 RNA Ligase I (TRL-BE101), which is relevant for applications in antibody drug discovery, gene editing, and mRNA therapeutics. Their proprietary SAMS™ platform enhances protein design and enzymatic studies, ensuring products meet rigorous quality standards for bioactivity and purity.
Reference
Product
T4 RNA Ligase I (TRL-BE101) – KACTUS
Ligaco
Brno, Czechia
A
1-10 Employees
2016
Key takeaway
The company is establishing Ligaco IT, s.r.o. in the Czech Republic, indicating its commitment to expanding its software solutions and digitalization expertise. Additionally, they have set up Ligas Consulting in the UK, which focuses on IT architecture, further showcasing their dedication to helping businesses adapt to technological advancements.
Reference
Core business
Ligaco - About
biotechrabbit GmbH
Berlin, Germany
A
11-50 Employees
2011
Key takeaway
biotechrabbit offers a range of ligases and nucleic acid modifying enzymes, including T4 DNA Ligase, which could be highly beneficial for your projects.
Reference
Product
biotechrabbit | Ligases & NA Modifying Enzymes - Enzymes and Proteins - Products | leap and lead
Fagus Antibody Services
Oxford, United Kingdom
A
1-10 Employees
2022
Key takeaway
The company, Fagus Antibody Services, offers a comprehensive service that includes the development and purification of antibodies, highlighting their expertise in antibody-related science. They also provide a product related to the query, specifically DNA Ligase III Rabbit pAb, which is crucial for DNA metabolism and involved in excision repair.
Reference
Product
DNA Ligase III Rabbit pAb - Fagus Antibody Services
LIG3 is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. DNA ligase 3 encoded by LIG3 is involved in excision repair and is located in both the mitochondria and nucleus, with
Technologies which have been searched by others and may be interesting for you:
Ligase is a type of enzyme that plays a crucial role in the process of DNA replication and repair. It facilitates the joining of two strands of DNA by forming a phosphodiester bond, effectively sealing nicks in the sugar-phosphate backbone of the DNA molecule. This enzyme is essential for maintaining the integrity of genetic material, particularly during cellular processes such as replication, transcription, and recombination. In addition, ligases are utilized in various biotechnological applications, including cloning and genetic engineering, where they assist in the assembly of DNA fragments.
Ligase plays a crucial role in DNA replication by facilitating the joining of DNA fragments. During replication, the DNA strand is synthesized in short segments known as Okazaki fragments on the lagging strand. DNA ligase is responsible for sealing the nicks and connecting these fragments, ensuring the integrity of the newly synthesized DNA strand. This enzyme catalyzes the formation of phosphodiester bonds between adjacent nucleotides. By doing so, it effectively creates a continuous DNA strand, which is essential for accurate genetic information transmission. Without ligase, the replication process would result in incomplete and unstable DNA, compromising cellular function.
1. DNA Ligase
DNA ligase is crucial for DNA replication and repair. It catalyzes the formation of phosphodiester bonds between adjacent nucleotides, sealing nicks in the DNA backbone, which is vital for maintaining genomic integrity.
2. RNA Ligase
RNA ligase is responsible for linking RNA molecules together. It plays a significant role in RNA processing, particularly in the formation of circular RNA and in certain viral replication processes.
3. T4 Ligase
T4 DNA ligase, derived from the T4 bacteriophage, is frequently used in molecular biology applications. It is known for its efficiency in joining blunt-ended and sticky-ended DNA fragments, making it ideal for cloning and recombinant DNA work.
4. E. coli Ligase
Ligase from E. coli is another important enzyme used in genetic engineering. It is particularly effective in repairing DNA and is often utilized in various laboratory techniques that require DNA manipulation.
Ligase plays a crucial role in molecular biology by facilitating the joining of DNA strands. This enzyme is essential for the processes of DNA replication and repair, as it seals nicks in the sugar-phosphate backbone of the DNA molecule, ensuring the integrity of the genetic information. Moreover, ligase is vital for recombinant DNA technology, as it enables the joining of DNA fragments from different sources, allowing for the creation of genetically modified organisms. Its ability to catalyze the formation of phosphodiester bonds between nucleotides is fundamental in various applications, including cloning, gene expression, and the construction of DNA libraries.
Ligase enzymes are crucial in various applications within biotechnology. They play a significant role in DNA replication and repair, facilitating the joining of DNA fragments. This is essential in cloning, where ligases are used to insert foreign DNA into plasmids, creating recombinant DNA molecules. In synthetic biology, ligases are employed to assemble multiple DNA fragments into a single construct. This process is vital for gene synthesis and the development of gene therapies. Additionally, ligases are utilized in diagnostics, particularly in techniques such as polymerase chain reaction (PCR) and next-generation sequencing, where they help ensure the integrity of DNA strands by sealing nicks and gaps.
Some interesting numbers and facts about your company results for Ligase
| Country with most fitting companies | United States |
| Amount of fitting manufacturers | 3659 |
| Amount of suitable service providers | 3406 |
| Average amount of employees | 11-50 |
| Oldest suiting company | 1990 |
| Youngest suiting company | 2022 |
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Some interesting questions that has been asked about the results you have just received for Ligase
What are related technologies to Ligase?
Based on our calculations related technologies to Ligase are Aromatics, Desiccants, Refrigerants, Resins, Green Chemistry
Who are Start-Ups in the field of Ligase?
Start-Ups who are working in Ligase are Fagus Antibody Services
Which industries are mostly working on Ligase?
The most represented industries which are working in Ligase are IT, Software and Services, Biotechnology, Other, Construction, Medical
How does ensun find these Ligase Companies?
ensun uses an advanced search and ranking system capable of sifting through millions of companies and hundreds of millions of products and services to identify suitable matches. This is achieved by leveraging cutting-edge technologies, including Artificial Intelligence.
