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Top Ligase Companies

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60 companies for Ligase

netwerk Ligant's Logo

netwerk Ligant

Hasselt, Belgium

A

11-50 Employees

2015

Key takeaway

Ligant is a network dedicated to children and young people with mental vulnerabilities, focusing on coordinated care and knowledge sharing through various programs and partnerships.

Highlighted product

Core business

Ligant | Home

FLUOROGENICS LIMITED's Logo

FLUOROGENICS LIMITED

Salisbury, United Kingdom

A

1-10 Employees

2011

Key takeaway

The company offers a range of products including the NEBNext UltraExpress™ FS DNA Library Prep Kit, which utilizes a single enzyme mix for key processes like end prep and dA-tailing. Additionally, they highlight their expertise in assembly techniques, which may be relevant for those interested in ligation strategies.

Highlighted product

Product

Ligase Quality | NEB

Ligare Weboplossingen's Logo

Ligare Weboplossingen

Stiens, Netherlands

A

1-10 Employees

-

Key takeaway

Ligare specializes in creating web solutions for various devices, emphasizing a personalized approach to website development.

Highlighted product

Core business

Ligare Weboplossingen – Websites met een persoonlijke aanpak

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Ligaco's Logo

Ligaco

Brno, Czechia

A

1-10 Employees

2016

Key takeaway

The company, Ligaco IT, s.r.o., is focused on providing top software solutions and has established Ligas Consulting in the UK, which specializes in IT architecture. With a strong background in digitalization and application development, they are well-equipped to support businesses in navigating technological advancements.

Highlighted product

Core business

Ligaco - Home

ArcticZymes Technologies ASA's Logo

ArcticZymes Technologies ASA

Tromsø, Norway

A

11-50 Employees

1990

Key takeaway

ArcticZymes Technologies specializes in enzymatic solutions, emphasizing their innovative ArcticZymes R2D Ligase™, the first ligase capable of ligating DNA to RNA. Their commitment to high-quality, customized enzymes enhances molecular research and therapeutics.

Highlighted product

Product

ArcticZymes R2D Ligase™ - ArcticZymes Technologies

ArcticZymes R2D LigaseTMnnArcticZymes RNA to DNA Ligase (ArcticZymes R2D LigaseTM) is the first ligase on the market that is able to ligate DNA to

Steinpilz Partner's Logo

Steinpilz Partner

Berlin, Germany

A

1-10 Employees

-

Key takeaway

LIGANT is a law firm specializing in real estate and commercial law, offering comprehensive legal advice, particularly in contract creation and enforcement related to architect and engineering law. Their membership in IGAL enhances their expertise through collaboration with a global network of professionals.

Highlighted product

Product

Lösungsorientiert – Ligant

Ligist's Logo

Ligist

Stockholm, Sweden

A

1-10 Employees

2001

Key takeaway

Ligist is a commercial film production company that has been active for two decades, emphasizing a commitment to environmentally sustainable practices and the protection of personal integrity and data throughout the production process.

Highlighted product

Service

Service - Ligist

Codexis's Logo

Codexis

Temecula, United States

B

51-100 Employees

2002

Key takeaway

Codexis has developed a new engineered ligase, CDX Ligase, which significantly enhances ligation efficiency, library yield, and complexity, addressing key challenges in sequencing. Their focus on innovative enzyme solutions aims to improve the production and quality of mRNA and other biopharmaceuticals.

Highlighted product

Product

CDX Ligase (Pre-commercial) :: Codexis, Inc. (CDXS)

A newly engineered ligase to address sequencing challenges by delivering higher ligation efficiency, library yield and complexity.

Ligero Logistics's Logo

Ligero Logistics

Kolkata, India

D

11-50 Employees

2020

Key takeaway

Ligero Logistics specializes in providing tailored supply chain solutions, making it well-equipped to handle complex logistical requirements. Their commitment to customized service and strong global partnerships ensures competitive rates and efficient operations, positioning them as a reliable end-to-end logistics partner.

Highlighted product

Core business

Ligero Logistics | Your End to End Logistics Partner!

Ligero Logistics works 24/7 to fulfill market requirements. Modern warehousing is available and forms the backbone of our customer service commitment. This is supported by a large fleet and freight forwarding services.

LIG Consultants's Logo

LIG Consultants

Canton, United States

B

1-10 Employees

2010

Key takeaway

LIG Consultants specializes in energy consulting, project management, and engineering services, which may relate to the broader context of ligase in energy-related applications.

Highlighted product

Core business

LIG Consultants | Energy Consulting, Project Management, and Engineering Services


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Things to know about Ligase

What is Ligase?

Ligase is a type of enzyme that plays a crucial role in the process of DNA replication and repair. It facilitates the joining of two strands of DNA by forming a phosphodiester bond, effectively sealing nicks in the sugar-phosphate backbone of the DNA molecule. This enzyme is essential for maintaining the integrity of genetic material, particularly during cellular processes such as replication, transcription, and recombination. In addition, ligases are utilized in various biotechnological applications, including cloning and genetic engineering, where they assist in the assembly of DNA fragments.


How does Ligase function in DNA replication?

Ligase plays a crucial role in DNA replication by facilitating the joining of DNA fragments. During replication, the DNA strand is synthesized in short segments known as Okazaki fragments on the lagging strand. DNA ligase is responsible for sealing the nicks and connecting these fragments, ensuring the integrity of the newly synthesized DNA strand. This enzyme catalyzes the formation of phosphodiester bonds between adjacent nucleotides. By doing so, it effectively creates a continuous DNA strand, which is essential for accurate genetic information transmission. Without ligase, the replication process would result in incomplete and unstable DNA, compromising cellular function.


What are the different types of Ligase enzymes?

1. DNA Ligase
DNA ligase is crucial for DNA replication and repair. It catalyzes the formation of phosphodiester bonds between adjacent nucleotides, sealing nicks in the DNA backbone, which is vital for maintaining genomic integrity.

2. RNA Ligase
RNA ligase is responsible for linking RNA molecules together. It plays a significant role in RNA processing, particularly in the formation of circular RNA and in certain viral replication processes.

3. T4 Ligase
T4 DNA ligase, derived from the T4 bacteriophage, is frequently used in molecular biology applications. It is known for its efficiency in joining blunt-ended and sticky-ended DNA fragments, making it ideal for cloning and recombinant DNA work.

4. E. coli Ligase
Ligase from E. coli is another important enzyme used in genetic engineering. It is particularly effective in repairing DNA and is often utilized in various laboratory techniques that require DNA manipulation.


Why is Ligase important in molecular biology?

Ligase plays a crucial role in molecular biology by facilitating the joining of DNA strands. This enzyme is essential for the processes of DNA replication and repair, as it seals nicks in the sugar-phosphate backbone of the DNA molecule, ensuring the integrity of the genetic information. Moreover, ligase is vital for recombinant DNA technology, as it enables the joining of DNA fragments from different sources, allowing for the creation of genetically modified organisms. Its ability to catalyze the formation of phosphodiester bonds between nucleotides is fundamental in various applications, including cloning, gene expression, and the construction of DNA libraries.


What applications use Ligase in biotechnology?

Ligase enzymes are crucial in various applications within biotechnology. They play a significant role in DNA replication and repair, facilitating the joining of DNA fragments. This is essential in cloning, where ligases are used to insert foreign DNA into plasmids, creating recombinant DNA molecules. In synthetic biology, ligases are employed to assemble multiple DNA fragments into a single construct. This process is vital for gene synthesis and the development of gene therapies. Additionally, ligases are utilized in diagnostics, particularly in techniques such as polymerase chain reaction (PCR) and next-generation sequencing, where they help ensure the integrity of DNA strands by sealing nicks and gaps.


Insights about the Ligase results above

Some interesting numbers and facts about your company results for Ligase

Country with most fitting companiesNetherlands
Amount of fitting manufacturers2576
Amount of suitable service providers2674
Average amount of employees1-10
Oldest suiting company1990
Youngest suiting company2020

Geographic distribution of results





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Frequently asked questions (FAQ) about Ligase Companies

Some interesting questions that has been asked about the results you have just received for Ligase

Based on our calculations related technologies to Ligase are Aromatics, Desiccants, Refrigerants, Resins, Green Chemistry

Start-Ups who are working in Ligase are Ligero Logistics

The most represented industries which are working in Ligase are IT, Software and Services, Other, Construction, Biotechnology, Logistics, Supply Chain and Transportation

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