Prime editing is a new gene-editing tool that combines the two most popular gene-editing technologies, CRISPR and base editing, to make precise edits to DNA and RNA. It uses a special enzyme, called Cas13, to make targeted changes to a gene sequence. Prime editing can make precise changes to DNA or RNA, including inserting, deleting, or swapping one or more base pairs in a gene sequence. It can also make changes to individual nucleotides, allowing for more flexibility than other gene-editing techniques. This technology has the potential to revolutionize gene-editing and improve the accuracy and efficiency of gene-editing therapies.