Quanta BioDesign

Who is Quanta BioDesign?

Quanta BioDesign is the inventor of SuperHydrophilic™ dPEG® technology used to make superior life science reagents and assays. Quanta BioDesign's building blocks and protected linkers enable SuperHydrophilic™ constructs and peptide modifications via our world-famous dPEG® products. Our simple-to-use products transform hydrophobic peptides into hydrophilic products. Moreover, the single molecular weight, discrete-length PEG chain (i.e., dPEG®) simplifies peptide analysis compared to dispersed PEG linkers that contain a range of PEG chain lengths and molecular weights. Our Life Science Department utilizes the superior power of dPEG® Technology; setting our products apart from similar research tools.

This company is:

Manufacturer

United States

11-50 Employees

Founding year: 1999

Products & services of Quanta BioDesign

Product

Verified

DBCO-amine - Quanta BioDesign

DBCO-amine, product number 11750, is an aza-dibenzocyclooctyne (DBCO) product used for strain-promoted azide-alkyne cycloaddition (SPAAC, also known as "copper free click chemistry"). The DBCO moiety reacts selectively with azides via SPAAC to form stable triazole linkages. The amine terminus of the molecule reacts with carboxylic acids and the active esters of carboxylic acids to form amide bonds. Insoluble in water, DBCO-amine is slightly soluble to sparingly soluble in most organic solvents. Quanta BioDesign, Ltd. recommends dimethylsulfoxide (DMSO), N,N'-dimethylformamide (DMF), or N,N'-dimethylacetamide (DMAC) as solvents for this product. DBCO-amine is relatively insensitive to bases and can be used in the presence of aqueous bases. This product is acid sensitive. It should not be subjected to pH < 5 during reaction or workup. The product should always be stored at -20°C when not in use.

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Goat anti-Human IgG (H&L), AQuora® 650 - Quanta BioDesign

AQuora® 650-labeled Goat anti-Human IgG (H&L) is suitable for use in immunodetection applications. The Goat anti-Human IgG (H&L) antibody has been covalently labeled with a cyanine-based dye utilizing our exclusive SuperHydrophilic technology, designed to improve solubility and reduce non-specific binding, while maintaining photophysical properties of spectrally comparable dyes (Alexa Fluor® 647, Cy5, and DyLight® 650). Alexa Fluor® and DyLight® are registered trademarks of Thermo Fisher Scientific.

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Propargyl amine - Quanta BioDesign

Propargyl amine, product number 10510, is an amine-functionalized, three-carbon, terminal aliphatic alkyne. A non-dPEG® product, propargyl amine (formally, prop-2-yn-1-amine) is an alkynyl partner for Quanta BioDesign's azide-functionalized dPEG®-based click chemistry reagents. Click chemistry using propargyl amine and azides requires catalysis. Copper(I) catalysis leads to the 1,3-dipolar cycloaddition product. Ruthenium catalysis forms the 1,5-dipolar cycloaddition product. The terminal amine can be reacted with any of Quanta BioDesign's dPEG® NHS or TFP esters or carboxylic acid products to form any desired product. To see a list of all of our click chemistry products, please click this link.

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Keywords

Medical

Pharmaceutical

Scientific Research and Development Services

Health Care

Biotechnical research, commercial

Biotechnology

Professional, Scientific, and Technical Services

Industries

Chemicals

Use Cases of Quanta BioDesign

Figure 4, 10524&10278, Click Chemistry Application 1a - Quanta BioDesign

Figure 4: Mixed surface coating of PN10524, azido-dPEG®11-amine, and PN10278, m-dPEG®8-amine. See the text for a discussion of the rationale for creating this construct. Compared to Figure 2, above, the surface azide groups in this construct are less crowded.

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