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imusyn GmbH & Co. KG
Hanover, Germany
A
11-50 Employees
2001
Key takeaway
Imusyn is a biotechnology company that specializes in alloproteomics, focusing on advancing allogeneic cellular therapies and personalized medicine. They offer innovative, high-throughput services for confirming target peptides, including protein engineering and production.
Reference
Product
Protein Engineering - imusyn GmbH & Co. KG
Proteinea
Town of Middletown, United States
B
11-50 Employees
2019
Key takeaway
Proteinea is revolutionizing protein engineering by utilizing advanced deep-learning models, particularly their Ankh protein language model, which enhances the design of biotherapeutics. Their innovative approach incorporates reinforcement learning and AI-based tools to optimize the efficacy and safety of therapeutic proteins, paving the way for smarter and faster development in this field.
Reference
Core business
PROTEINEA - Charging the future of biologics to tackle life-threatening diseases
We make biotherapeutics design smarter, safer, and faster by leveraging novel deep-learning models & platforms integrated with smart experimental throughput.
GeneFrontier Japan
Sakai, Japan
A
- Employees
2010
Key takeaway
The company specializes in protein engineering and biologics, utilizing phage display technology to develop innovative therapeutic antibodies and new biopharmaceutical candidates. Their expertise includes designing small molecules from cyclic peptides, highlighting their focus on advanced drug discovery.
Reference
Product
Drug Discovery | 日本語版
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Profacgen
Shirley, United States
B
- Employees
-
Key takeaway
Profacgen is a leading protein service provider that offers custom protein services, including the production of recombinant proteins and protein interaction analysis. With a wide range of expression systems and a professional team, they ensure high-quality data and rapid turnaround for both industrial and academic clients.
Reference
Core business
Profacgen, Perfect Protein
Navigo Proteins GmbH
Halle, Germany
A
11-50 Employees
2017
Key takeaway
Navigo Proteins is a leading protein engineering company that specializes in developing custom precision affinity ligands using selected protein scaffolds. Their expertise in protein engineering, particularly in creating innovative binder-proteins, enhances biotherapeutics development and commercial biologics manufacturing.
Reference
Core business
The protein engineering experts out of Halle/Germany
Navigo Proteins is a successful, steadily growing, privately held protein engineering company. We are developing best-in-class custom precision affinity ligands, based on selected protein scaffolds.
SeSaM-Biotech GmbH
Germany
A
1-10 Employees
2008
Key takeaway
SeSaM-Biotech specializes in Directed Enzyme Evolution, a key aspect of Protein Engineering, focusing on mutagenesis, assay development, and computational design to enhance enzyme properties. Their expertise and collaboration with RWTH Aachen University enable them to offer innovative solutions for improving enzymes used in various industrial applications.
Reference
Core business
Enzyme Evolution | A competitive edge for your enzymes - SeSaM-Biotech
SeSaM-Biotech provides enzyme services in form of Directed Enzyme Evolution, also known as Protein Engineering. Find out more about our specific services.
e-Proteins
Gembloux, Belgium
A
1-10 Employees
2012
Key takeaway
e-Proteins is a leader in the production of avidin derivatives, offering innovative binding proteins that enhance application performance. Their dedicated R&D team has developed standardized protocols and quality controls, ensuring reliable and high-quality products for various binding applications.
Reference
Core business
e-Proteins: A Solution of any biotin Binding application
e-Proteins is the world leader in avidin derivatives/binding protein production which are the best alternatives to Streptavidin.
Protera
Santiago, Chile
A
11-50 Employees
2018
Key takeaway
The company is revolutionizing the food industry by developing advanced functional ingredients through protein engineering and artificial intelligence. Their innovative approach ensures the creation of high-performance protein ingredients that are nutritious and effective under various conditions.
Reference
Core business
Home • Protera
We are building the next generation of functional ingredients for the food industry using protein engineering and artificial intelligence.
Leadgene Biomedical Inc.
Tainan, Taiwan
51-100 Employees
2013
Key takeaway
Leadgene Biomedical focuses on enhancing Taiwan's biotech industry through innovative R&D and manufacturing expertise, particularly in the development of cutting-edge antibodies and proteins. Their commitment to technological innovation positions them as a key player in accelerating biomedical progress.
Reference
Product
Leadgene Biomedical
Accelerate biomedical progress with our innovative R&D and manufacturing expertise; elevate your research with our cutting-edge antibodies & proteins development.
Bioingenium s.l.
Barcelona, Spain
A
11-50 Employees
2006
Key takeaway
The company is a leading expert in the Pichia pastoris system, specializing in recombinant protein production with the capability to scale up to grams of high-quality, endotoxin-free proteins. They also conduct preliminary protein production studies in CHO and HEK cells.
Reference
Core business
Home - Bioingenium
Your CDMO for protein expression Learn about us Discover our services Our technology platforms Bacterial expression With our platform, recombinant protein production can be easily scale up to obtain up to grams of soluble purified, endotoxin free protein with certificate of analysis. Learn more Mammalian cell expression Our platform offers fast production of high quality […]
Technologies which have been searched by others and may be interesting for you:
Protein engineering involves the design and construction of new proteins or the modification of existing ones to enhance their properties or functionalities. This scientific discipline integrates concepts from molecular biology, biochemistry, and bioinformatics to manipulate protein structure. By altering amino acid sequences, researchers can create proteins with improved stability, activity, or specificity for various applications, including pharmaceuticals, biotechnology, and industrial processes. The advancements in protein engineering have significant implications for drug development, enzyme production, and the creation of novel biomaterials.
Protein engineering plays a crucial role in drug development by enabling the design and modification of proteins to optimize their therapeutic potential. Through techniques such as site-directed mutagenesis and protein design algorithms, scientists can alter protein structures to enhance their stability, specificity, and efficacy. This tailored approach allows for the creation of more effective drugs that can target specific biological pathways, reducing side effects and improving patient outcomes. Additionally, protein engineering facilitates the development of biopharmaceuticals, including monoclonal antibodies and enzyme replacements. These engineered proteins can be designed to bind more effectively to their targets, leading to innovative treatments for diseases such as cancer and genetic disorders. By leveraging the principles of protein engineering, researchers can accelerate the drug discovery process, ultimately bringing safer and more effective therapies to market faster.
Protein engineering employs several advanced techniques to modify and design proteins for specific functions.
1. Site-Directed Mutagenesis
This technique allows for precise alterations in the DNA sequence of a gene, enabling targeted changes to specific amino acids in the protein. By introducing mutations, researchers can study the effects on protein function and stability.
2. Directed Evolution
In this process, proteins are subjected to iterative rounds of mutation and selection. By mimicking natural selection in a lab setting, scientists can evolve proteins with desirable traits, such as enhanced activity or stability under extreme conditions.
3. Computational Modeling
Utilizing computer algorithms, researchers can predict the structure and stability of protein variants. This method helps in designing proteins that are more efficient or have new functionalities by simulating how changes in their sequence affect their three-dimensional structure.
4. Chimeric Protein Construction
This technique involves combining segments from different proteins to create hybrid proteins. By fusing parts that confer specific properties, researchers can design proteins with enhanced characteristics, such as improved catalytic activity or altered binding affinity.
These techniques collectively contribute to advancing the field of protein engineering, allowing for innovations in pharmaceuticals, biotechnology, and various industrial applications.
Protein engineering plays a crucial role in biotechnology by enabling the design and modification of proteins for specific functions. This process enhances the performance of enzymes used in industrial applications, improves the efficacy of pharmaceutical drugs, and allows for the development of new therapeutics. By manipulating protein structures, researchers can create molecules that exhibit increased stability, activity, or specificity, leading to advancements in drug discovery and development. Moreover, protein engineering contributes to the production of biologics, including monoclonal antibodies and vaccines, which are essential in the treatment and prevention of diseases. This technology also facilitates the creation of biosensors and biofuels, showcasing its versatility and significance across various biotechnological fields. In summary, the importance of protein engineering in biotechnology lies in its ability to innovate and optimize biological systems for a wide range of applications.
The field of protein engineering encounters several significant challenges that can complicate the development of effective proteins. One primary obstacle is the complexity of protein folding and stability. Achieving the correct three-dimensional structure is crucial, yet predicting how a protein will fold based on its amino acid sequence remains a difficult task. Additionally, designing proteins to perform specific functions often requires extensive trial and error, making the process time-consuming and resource-intensive. Another challenge is the difficulty in replicating natural post-translational modifications, which can affect protein activity and efficacy. These factors necessitate innovative approaches and advanced technologies to streamline the protein engineering process and enhance the overall success rate.
Some interesting numbers and facts about your company results for Protein Engineering
| Country with most fitting companies | United States |
| Amount of fitting manufacturers | 6480 |
| Amount of suitable service providers | 6792 |
| Average amount of employees | 11-50 |
| Oldest suiting company | 2001 |
| Youngest suiting company | 2019 |
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Some interesting questions that has been asked about the results you have just received for Protein Engineering
What are related technologies to Protein Engineering?
Based on our calculations related technologies to Protein Engineering are Biomedical (Red), Bioinformatics (Gold), Environmental Biotechnology (Grey), Agricultural Biotechnology (Green), Food Related Biotechnology (Yellow)
Which industries are mostly working on Protein Engineering?
The most represented industries which are working in Protein Engineering are Biotechnology, Other, Manufacturing, IT, Software and Services, Pharmaceuticals
How does ensun find these Protein Engineering Companies?
ensun uses an advanced search and ranking system capable of sifting through millions of companies and hundreds of millions of products and services to identify suitable matches. This is achieved by leveraging cutting-edge technologies, including Artificial Intelligence.
