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Guilford, United States
51-100 Employees
2013
Quantum-Si’s Next Generation Protein Sequencing Technology Enables Rapid and Accurate Distinction of Variants of the SARS-CoV-2 Virus. Quantum-Si and Researchers to Highlight the Power of Next-Generation Protein Sequencing™ on Platinum® at US HUPO Conference. Quantum-Si Reports Fourth Quarter and Full Year 2023 Financial Results. Detecting single amino acids through binding kinetics, the innovative Platinum® benchtop sequencer is highly sensitive to protein variants, enabling deep interrogation of proteins to deliver breakthrough insights.
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Featured
Unlock the Power of Next-Generation Protein Sequencing
... Interrogate features of the proteome in your own lab with confidence using our next-generation protein sequencing technology. Learn more here! ...
San Diego, United States
11-50 Employees
2015
So we are biased towards bold action backed by thoughtful decisions. Encodia’s leadership team has an unparalleled track record of developing and launching biotechnologies that empower the world’s most important discoveries. Our board guides the mission and vision at Encodia with sound and effective leadership. Provides in-depth information on cellular processes to enable personalized medicine. Join technology’s most innovative thinkers working to unlimit biology. Join technology’s most innovative thinkers working to unlock biology.
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Encodia
... ProteoCode™, our breakthrough reverse-translation technology, drives protein sequencing at scale to accelerate innovations in human health. ...
London, United Kingdom
11-50 Employees
1993
Our proteomics expertise provides complementary and enabling content and insight for our customers to develop more effective, time and cost-efficient healthcare solutions. To enable targeted therapeutics by delivering innovative proteomic services.
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Gel-Based Protein Sequencing
... Gel-Based Protein Sequencing ...
Shirley, United States
51-100 Employees
2005
Honestly, we are surprised by technical expertise and professional platform in Creative Proteomics. Our vision is to be the global leader in providing proteomics services and solutions. Creative Proteomics has gradually developed into an integrated company that provides proteomics, metabolomics, glycomics, and bioinformatics analysis services to researchers in the pharmaceutical, biotechnology, agriculture and nutrition industries, as well as academic and government organizations. With a continuing focus on quality, we are proud of satisfying the needs of our clients both at home and abroad covering more than 50 countries and districts. Our proteome analysis platform provides protein separation, characterization, identification and quantification services, featured with high throughput and super-sensitivity. We can provide a wide range of metabolomics services from discovery to targeted analysis. We continuously improve the quality to offer both industry-use and research-use services to support our global clients with high-quality results and exceptional customer support. They did provide us with the best data to meet our needs.”.
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Protein Sequencing by Mass Spectrometry
... Protein Sequencing by Mass Spectrometry - Creative ...
Boston, United States
1-10 Employees
2020
Manifold Bio is a therapeutics company with an unprecedented advantage in engineering precision biologics. Discover how our innovative platform unlocks the next generation of complex biologics across a range of therapeutic areas.
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Featured
M-Design Platform for Earlier In Vivo Testing | Manifold Bio
... Protein multiplexing via DNA sequencing ...
Rancho Santa Margarita, United States
1-10 Employees
2014
Battery Backup Power UPS Systems Provide Automatic Emergency Backup Power, Voltage Regulation, And 5 Tier Power Conditioning To NASA, Professional Racing Series, Server Farms, Data Centers, School Districts, 3D Printer Additive Manufacturing Facilities, Medical Offices, Small Businesses, Laboratories, And Universities. Most of our base systems can be customized by our factory in Costa Mesa, California to meet specific voltage, frequency, receptacle type, and power cord requirements. Our base systems come with maintenance free, valve regulated, sealed lead acid batteries, but we also offer optional long life lithium iron phosphate batteries upon request. Need help? Let our engineers do all the work to ensure you find a system that will work with your equipment and meet your backup time requirements. Customers are the most important part of any business.
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Battery Backup Uninterruptible Power Supply (UPS) And Power Conditioner For Applied Biosystems Procise Protein Sequencing System Quote Request
... Battery Backup Uninterruptible Power Supply (UPS) And Power Conditioner For Applied Biosystems Procise Protein Sequencing System Quote ...
Redditch, United Kingdom
11-50 Employees
1973
Established in 1973, AltaBioscience provides analytical laboratory services in addition to custom peptide synthesis, DNA oligos and both polyclonal and monoclonal antibodies. AltaBioscience manufactures and distributes all specialist biochemical products from its UK based ISO 9001:2015 laboratory and performs protein sequencing and amino acid analysis accredited to ISO 17025:2017 standard. We are pleased to provide custom production of peptide-oligonucleotide conjugates (POCs) with industry-leading turnaround times. Established in 1973, AltaBioscience provides analytical laboratory services in addition to custom peptide synthesis, DNA oligos, and polyclonal and monoclonal antibodies. AltaBioscience manufactures and distributes all specialist biochemical products from its UK-based ISO 9001:2015 laboratory and performs protein sequencing and amino acid analysis accredited to ISO 17025:2017 standards. AltaBioscience offers a premium service, starting with a consultation. With more than 40 years’ experience and UKAS certification to ISO/IEC 9001, AltaBioscience scientific analysis laboratory provides unrivalled expertise and accuracy. Amino acid analysis can help feed manufacturers develop cost-effective, nutritionally complete and consistent solutions for optimal animal nutrition.
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Experts in Amino Acid Analysis, Peptide Synthesis and Protein Sequencing
... Providing Amino Acid Analysis, Protein Sequencing and Custom Peptide Synthesis services globally, with a heritage dating back to 1973. ...
Hamburg, Germany
1-10 Employees
2019
We are also able to extract more RNA per cell when compared to other fixation methods.”. Anacyte Laboratories is committed to reaching and serving our customers on a global scale with services and products such as CellCover, a shield for cell fixation of DNA, RNA, proteins, and cell morphology. CellCover is the only reagent that allows parallel storage of proteins, RNA, and DNA in their cellular context. A unique and special feature of CellCover is the ability to perform additional molecular analysis on cells that have already been analyzed on a morphological or molecular level: DNA (e.g. CellCover is a non-toxic formulation, a formaldehyde alternative designed to protect the status of DNA, RNA, and protein expression and gene expression in human and animal cells and solid tissues, including tumors and cultured cells (adherent, suspension, spheroids). Chemical degradation is inhibited with CellCover as well, leading to exceptional protein stabilization and protein fixation, as well as RNA fixation and DNA fixation. CellCover is a key initial step for successful experiments in genome analysis, transcriptome analysis, and proteomic analysis. CellCover is a safe formaldehyde alternative fixation, with formalin sensitive epitopes readily accessible for antibodies in immunohistochemistry experiments.
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CellCover RNA, DNA, Protein Stabilization | Anacyte Laboratories
... CellCover, DNA & RNA stabilization modification solution & protein sequencing are all protected. RNA degradation is inhibited leading to great results in RNA sequencing or single-cell sequencing experiments. ...
Tustin, United States
11-50 Employees
Franek Technologies in Tustin, CA is an ISO 9001:2015 registered company, a Minority-and Woman-Owned Business, and one of the worldwide leaders in UPS backup power for laboratory equipment. Franek Technologies scientific LPS/UPS instrument support applications include:. Our mission is to service the vital work being done in laboratories worldwide for analytical, research and diagnostic purposes. At Franek Technologies, we have established a reputation within the medical and research laboratory communities for reliable power protection supplies. Franek Technologies has a long history of delivering reliable UPS devices that can power any machine or equipment regardless of the working conditions. We have 35 years of experience in laboratory instrumentation systems applications. We specialize in providing complete UPS systems for laboratory equipment for analytical, diagnostics, forensic, life science, pharmaceutical and biotechnology instrumentation systems applications. Using decades of engineering, manufacturing, and customer service expertise, we go the extra mile in understanding our customers’ applications, needs and operational constraints.
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Featured
Procise C-Terminal Protein Sequencing System - Franek Technologies, Inc.
... Procise C-Terminal Protein Sequencing System - Franek Technologies, Inc. ...
Leuven, Belgium
1001-5000 Employees
1982
Together we take on the challenges of tomorrow. Our venturing ecosystem supports tech entrepreneurs by providing them with funds and knowhow. A selection of our mature technologies is available for immediate application in research and industry. Take a look at how the goal of a sustainable future guides our research and our internal organization.
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Featured
Digiome: realizing the promise of nanopore protein sequencing
... Single-molecule protein sequencing would mean a leap forward for life sciences and therapeutics. The Digiome project is all about making that happen. ...
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Some interesting numbers and facts about the results you have just received for Protein Sequencing
| Country with most fitting companies | United States |
| Amount of fitting manufacturers | 18 |
| Amount of suitable service providers | 14 |
| Average amount of employees | 11-50 |
| Oldest suiting company | 1973 |
| Youngest suiting company | 2020 |
Protein sequencing is the process of determining the precise order of amino acids in a protein molecule. This technique is fundamental in biochemistry and molecular biology, serving as a cornerstone for understanding protein structure, function, and evolution. By elucidating the amino acid sequence, scientists can predict the three-dimensional shape of a protein, which is crucial for comprehending how proteins interact with other molecules within a cell. The insights gained from protein sequencing have profound implications across various fields, including drug discovery, where knowledge of a protein's sequence can aid in the design of molecules that can modulate protein function. Moreover, protein sequencing is instrumental in the study of genetic diseases, as mutations leading to changes in amino acid sequences can disrupt protein function, contributing to disease pathology. The advent of advanced technologies such as mass spectrometry and bioinformatics tools has significantly accelerated protein sequencing, allowing for the rapid analysis of complex protein mixtures. This progress underscores the importance of protein sequencing in advancing our understanding of biological systems and in developing therapeutic strategies for treating diseases. Through its ability to provide detailed insights into the molecular building blocks of life, protein sequencing remains a critical tool in the expanding field of proteomics, the large-scale study of proteins, which is pivotal for unraveling the complexities of cellular processes and disease mechanisms.
1. Precision in Identification
Protein sequencing allows for the precise identification of amino acid sequences in proteins. This accuracy is crucial for understanding protein functions and interactions within biological systems, setting it apart from techniques that offer only partial insights.
2. Disease Diagnosis and Research
The method plays a pivotal role in the diagnosis of genetic and protein-related diseases. By identifying mutations or abnormalities in protein sequences, it facilitates targeted therapies and advances in medical research, offering a significant advantage over less specific diagnostic tools.
3. Evolutionary Insights
Protein sequencing can reveal evolutionary relationships between species by comparing their protein sequences. This ability to trace evolutionary paths and understand functional conservation across different organisms provides a unique perspective that alternative methods lack.
4. Drug Development
It is instrumental in drug discovery and development. By understanding the exact structure of target proteins, researchers can design drugs that precisely interact with their intended targets, enhancing the efficacy and reducing side effects compared to approaches that do not utilize this level of detailed information.
While evaluating the different suppliers make sure to check the following criteria:
1. Technology and Equipment
Ensure the supplier has the latest technology and equipment for protein sequencing, which can significantly affect accuracy and speed.
2. Experience and Expertise
Consider the supplier's experience in the field and the expertise of their team in handling complex protein sequencing projects.
3. Data Analysis and Reporting
Evaluate their capability in data analysis and the comprehensiveness of their reporting. Detailed reports can provide valuable insights for your research or project.
4. Quality Control Measures
Check the quality control measures in place to ensure the reliability and accuracy of the sequencing results.
5. Turnaround Time
Consider the supplier's average turnaround time for projects similar to yours. Faster results can expedite your research or product development.
6. Cost
Compare the cost of services among suppliers, but ensure that this does not compromise the quality of the sequencing results.
7. Customer Support
Good customer support is crucial for addressing any queries or issues that may arise during the sequencing process.
Pharmaceuticals and Biotechnology In the pharmaceutical and biotech industries, protein sequencing plays a pivotal role in drug discovery and development. By identifying the amino acid sequence of proteins involved in diseases, companies can design drugs that specifically target these molecules. This precision helps in creating more effective and safer medications, reducing the time and cost associated with drug development. Agriculture In agriculture, protein sequencing is used to enhance crop resistance and nutritional value. By understanding the protein makeup of plants, scientists can engineer crops that are more resilient to pests, diseases, and environmental stresses. This use case not only increases food security but also supports the development of crops with improved nutritional profiles, catering to the global demand for high-quality food sources. Environmental Science Environmental scientists utilize protein sequencing to monitor and assess biodiversity and ecosystem health. By sequencing proteins from various organisms, researchers can track changes in species populations and identify the presence of pollutants or pathogens in the environment. This information is critical for conservation efforts and in devising strategies to mitigate environmental degradation. Each of these use cases demonstrates the versatility and impact of protein sequencing across different sectors, highlighting its importance in driving innovation and addressing global challenges.
Protein sequencing technology, pivotal in understanding the amino acid sequences of proteins, has advanced significantly, positioning it predominantly at TRL 6 to 7 in the current landscape. This classification stems from the successful demonstration of protein sequencing techniques in relevant environments, particularly through mass spectrometry and Edman degradation, which have become the cornerstones in this field. The evolution towards higher TRLs is marked by the integration of high-throughput methodologies, enabling the analysis of complex biological samples with unprecedented depth and sensitivity. However, challenges related to sequencing completeness, particularly with respect to post-translational modifications and the identification of novel amino acids, prevent it from reaching the highest TRLs. The difficulty in accurately quantifying all forms of protein modifications and the need for sophisticated, yet user-friendly analytical tools underscore the technical hurdles. Moreover, the intricate nature of proteins, with their vast diversity and complexity, necessitates further refinement in both computational algorithms for data analysis and the enhancement of detection technologies to achieve greater accuracy and throughput. These ongoing technical developments and the endeavor to overcome existing limitations are essential for transitioning protein sequencing technology to full commercial application and widespread adoption, reflecting its current position in the TRL spectrum.
In the Short-Term, protein sequencing is expected to benefit significantly from advancements in mass spectrometry and AI-driven algorithms. These technologies will enhance accuracy and reduce the time required for sequence determination. The integration of machine learning models is predicted to improve the prediction of protein structures from sequences, allowing for more rapid and cost-effective research applications. This phase marks a pivotal shift towards more personalized medicine, as the ability to quickly sequence proteins from individual patients becomes more accessible. Moving into the Mid-Term, we foresee the development of more sophisticated bioinformatics tools that will enable the handling of vast datasets generated by next-generation sequencing technologies. This will facilitate not only the sequencing of proteins at a granular level but also the understanding of their complex interactions within biological systems. The mid-term advancements are expected to unlock new pathways in drug discovery and the development of novel therapeutic strategies, bridging gaps in current medical treatments. In the Long-Term, the focus will likely shift towards the integration of protein sequencing into nanotechnology and the development of highly specific biosensors. These sensors could detect changes at the molecular level, offering unprecedented insights into protein dynamics in real-time. Such advancements could revolutionize disease diagnosis and the monitoring of patients' responses to treatment, opening new frontiers in personalized and precision medicine. Furthermore, the long-term developments promise to expand our understanding of the proteome, potentially leading to breakthroughs in how we treat complex diseases.
