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Verified
Synthetic Biology | EcoNexus
Synthetic Biology | Related Publications | Genetically engineered gene drives: IUCN report on Synthetic Biology lacks balance | gene-drives-2021_critique-of-iucn-report.pdf | gene-drives-2021_critique-of-iucn-report_summary.pdf | Gene Drives - a report on their science, applications, social aspects, ethics and regulations | gene-drives-report.pdf | summary-gene-drives-report.pdf | New Genetic Engineering Techniques: Precaution, Risk, and the Need to Develop Prior Societal Technology Assessment | Steinbrecher & Paul Precaution and NGETs Environment AM 2017.pdf | Synthetic biology: A continuing challenge for the CBD | Potential Impacts of Synthetic Biology on the Biodiversity | CSOsynbiosubmission_CBD_SBSTTA_synbio.pdf | Synthetic Biology needs urgent attention from the SBSTTA | econexus-synthetic-biology-submission.pdf | Synthetic Biology
by EcoNexus
Verified
Synthetic Biology Workstation - Hudson Robotics, Inc.
Synthetic Biology Hudson's new Synthetic Biology Workstation automates the entire portion of the pipeline from Gene Assembly through Plasmid Preparation. Part of our new series of instruments designed to support the Synthetic Biology Pipline All of these functions are automated and integrated into a single, easy to use system. Pipetting/Hit Picking DNA Normalization Transformations
by Hudson Robotics
Verified
Synthetic biology | Cambridge Consultants
Synthetic biology | Scientific excellence with commercial acumen | Background in biodesign | Antha expertise | Accelerating development | Synthetic biology labs | SGI BioXP 3200 | News & insights | Cambridge Consultants’ world-class designers recognized with two iF DESIGN AWARDS | How digital twins can help confront the challenges of scaling up cultured protein | Bioprocessing meets machine learning: the conversation that is driving a cell therapy breakthrough | Quantum computing for pharma and life sciences – opportunities are on the horizon | Events | Medtech Connect | The medtech innovation ecosystem of the future
by Cambridge Consultants
Verified
Synthetic Biology: Biotechnology Consulting | BCG
From food and pharma to construction, BCG synthetic biology consultants help clients build biotech capabilities to drive new disruptive strategies.
by The Boston Consulting Group
Verified
Systems Biology and Synthetic Biology – Brown Technical Books
The genomic revolution has opened up systematic investigations and engineering designs for various life forms. Systems biology and synthetic biology are emerging as two complementary approaches, which embody the breakthrough in biology and invite application of engineering principles. Systems Biology and Synthetic Biol
by Brown Technical Media Corp.
Verified
DiscovIR-GC™ Solutions for Metabolomics & Synthetic Biology - Spectrometrics - The Chemistry of Collaboration
DiscovIR-GC™ with parallel Mass Spectrometry is a uniquely powerful platform for metabolite annotation and unknown/biomarker identification. By combining chromatographic separation with mass spectrometry and solid-phase FTIR, a structurally informative spectroscopic technique, the DiscovIR-GC™ delivers enhanced Metabolomics Standards Initiative (MSI) Level 2 Annotation, even in complex mixtures/matrices: applications where offline metabolite extraction & purification, or preparative fraction collection for confirmatory NMR analysis, is impractical or impossible. For true unknowns, MS and IR spectra may be interpreted, to shortlist and rank candidate structures based on molecular formula and functional groups. This approach minimises the number, and cost, of commercially available, or synthesised standards, required to obtain MSI Level 1 identification. Potential DiscovIR-GC™ applications for metabolomics include the analysis of alkaloids, volatiles/semi-volatiles, terpenoids, FAMEs and simple lipids (sterols, alkanes, alkanols, wax esters, etc). Spectrometrics are the UK’s leading experts in GC-MS based metabolomics, with over 25-years’ experience running a metabolomics core facility and product managing metabolomics solutions and analysers. DiscovIR-GC™ for Metabolite ID email: [email protected]
by Spectrometrics Limited
Verified
Synthetic Biology : Tools and Applications– Booksmart
Synthetic Biology : Tools and Applications
by Booksmart
Verified
Fungal Genomics, Synthetic Biology and Bioprocess Development - Agile BioFoundry
The Agile BioFoundry houses a filamentous fungal and non-model yeast synthetic biology capability. This effort also comprises integrated fungal genetic tool and medium scale (15-120L) bioprocess development capability. Samples for Testing and Learning by a systems biology approach are generated from large shake flask experimental capabilities or through one of our stirred tank reactors that […]
by Agile BioFoundry
Verified
A Novel Synthetic Biology Platform for Controlling Gene Expression | YEDA Technology Transfer
OverviewA method for controlling gene expression using a novel phage-based transcription factor-peptide system. , Background and Unmet NeedA fundamental challenge of synthetic biology and its clinical applications is the capability to control gene expression. Presently, gene expression systems for research and industry have several limitations, such as a small number of available systems, inconsistent behavior among systems, lack of sufficient dynamic range of expression, and the requirement for high concentrations of a signaling molecule to induce/repress a gene. Consequently, there is a strong need for a better and diverse array of gene expression systems. , The SolutionThe team of Prof. Sorek at the Weizmann Institute of Science (WIS) has made the paradigm – shifting discovery that bacteriophages have a quorum sensing system, similar to that found in bacteria. The novel system, named Arbitrium by the Sorek team, communicates to said phages residing within bacteria, whether a lytic or lysogenic cycle is to be entered. Arbitrium system can be harnessed to a wide range of synthetic-biology and biotechnological applications. , Technology Essence Phages can infect bacteria either in a lytic cycle, which lyses the bacterial wall, or in a lysogenic cycle in which the phage genome integrates into the bacterial genome. The research team of Prof. Sorek discovered the novel Arbitrium communication system that enables lytic or lysogenic cycle (Fig. A). The Arbitrium system functions on the basis of three genes, aimR, aimP, and aimX. AimR is a dimeric receptor that binds and activates the transcription of gene aimX, whereby AimX inhibits lysogeny leading to lysis (Fig. B). AimP is a six amino acid pro-peptide (arbitrium peptide) that is expressed following infection, secreted extracellularly, and post-translationally modified. After the arbitrium peptide accumulates to a specific concentration, the arbitrium peptide is internalized and bound by the AimR receptor, which inhibits the expression of AimX and leads to lysogeny (Fig. C). The Sorek team further determined that when infected bacteria are incubated with the arbitrium peptide from the same phage that infected them, the bacterial growth curve changes due to a shift to a lysogenic cycle (Fig. D). However, when incubated with an arbitrium peptide from a different phage, the bacterial growth curve does not shift, regardless of peptide concentration (Fig. E). , Applications and AdvantagesUnique system – Effectively induces or shuts off expression of a gene. Standard Chemistry – Uses regular six amino acid peptides, therefore standard synthesis can be used. Wide Dynamic Range Over 100 Different Systems Uniformity Among Systems Schematic of arbitrium peptide accumulation during phage infection of bacteria. B) Post-infection aimR and aimP expression leading to lysis and AimP accumulation. C) At later stages after infection, lysogeny is preferred due to inhibition of AimX expression. D-E) Growth curves of B. subtillis in the presence of Phage SP Beta with either its corresponding arbitrium peptide (D) or arbitrium peptide from the phi3T phage (E). (Image modified from Erez Z, et al. Nature. 2017 Jan 26;541(7638):488-493. doi: 10.1038/nature21049. Epub 2017 Jan 18) , ReferencesErez, Zohar, Ida Steinberger-Levy, Maya Shamir, Shany Doron, Avigail Stokar-Avihail, Yoav Peleg, Sarah Melamed, et al. 2017. “Communication between Viruses Guides Lysis-Lysogeny Decisions.” Nature 541 (7638): 488–93.
by Yeda Research and Development Co. Ltd
Verified
Synthetic Biology Market Size, Share, Trends, Opportunities, & Forecast
Synthetic Biology Market size was valued at USD 10.42 Bn in 2021 and is projected to reach USD 63.78 Bn by 2030, growing at a CAGR of 22.33%
by Verified Market Research
Boston, United States
1-10 Employees
2013
Lattice provides analytics so customers can make sense of large data sets. Lattice provides formalized, domain specific specification languages so customers can describe designs and automatically capture rules. Lattice provides tools to store and share in-silico bio-designs with a range of LIMS, databases, and synthesis providers. We license state-of-the-art bio-design automation software configured, deployed, and secured to fit your needs. We connect customers to service providers through flexible APIs and engagement models. They expertly met our requirements and their delivery on change requests were lightning-fast. Lattice has provided a high level of engagement from day 1 and would be a tremendous complement to any in-house software engineering team.". We use experimental data and institutional knowledge to enable bio-design productivity and learning.
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Featured
Lattice | Software for synthetic biology
... Lattice | Software for synthetic biology ...
Frankfurt, Germany
51-100 Employees
2019
We are building a new & superior Synthetic Biology operating system - unlocking the global impact of sustainable and cost-competitive production. Synbionik’s scientific units jointly develop efficient concepts for the manufacturing of the microorganism and / or natural substance. Synbionik provides ongoing support with the know-how gained in the process. Synthetic Biology is the sustainable and potentially cost-efficient production of compounds through genetic engineering in microorganisms. Flexible basis for the production of various compounds that is available off-the-shelf. We constantly improve our bio-factories and processes to offer you solutions that fit your budget and that accelerate the time to market. Our operating system allows the design and construction of microorganisms to manufacture a molecule from simple and low-cost substrates, thereby enabling cost-effective processes. Ideas, internal or based on customer inquiries, are evaluated with focus on the economic value and technical feasibility and freedom to operate.
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Featured
We are Synbionik, the emerging European leader in Synthetic Biology
... We convert it via genetic engineering into a superior operating system vs. existing Synthetic Biology operating systems Cheaper and more efficient production Flexible basis for the production of various compounds that is available off-the-shelf Novel IP, leading to protection vs. ...
Bengaluru, India
1-10 Employees
Shilps Dexter TM Platform is uniquely suited for getting you the rare cells you want. Finding the rights cells is like looking for a needle in a haystack. For cell based pharmaceuticals, whether its cell therapies or biopharmaceuticals, getting the right cell is crucial. Our patented platform enables massively parallel functional interrogation of thousands of single cells - so that biologists can do what they are best at doing. We find the rare cells that work for novel therapeutics .
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Featured
For the Synthetic Biology Industry, whether it is bio enzymes, biofuels, lab grown meat or alternatives to plastic, the process starts with engineering cells.
... For the Synthetic Biology Industry, whether it is bio enzymes, biofuels, lab grown meat or alternatives to plastic, the process starts with engineering cells. ...
Copenhagen, Denmark
11-50 Employees
2018
We are a producer of Naloxone for reversing opioid overdose and in combination therapy for opioid use disorder. We are engaged in establishing a broader API portfolio and our team is researching growth areas that would benefit from advanced manufacturing and reinvention. Our pioneering production methods blend synthetic biology and traditional chemistry. Flexible intermediates in this proprietary synthetic pathway streamline the manufacture of a wide range of alkaloid molecules. These APIs represent the priority portfolio offering of River Stone Biotech. Our platform can be harnessed to realize market-leading positions on other alkaloid APIs through the introduction of revolutionary production methods. We work with a small number of global providers to establish a virtual, cross-functional operation that enables our API offering. Here, expert scientists perform high-quality research to innovate and to optimize production methods.
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Featured
Transforming Pharma with Synthetic Biology
... River Stone Biotech combines synthetic biology and traditional chemistry to reinvent the production of specialty molecules. Our priority focus is on active pharmaceutical ingredients (APIs) with proven utility in treating substance use disorders. ...
Boston, United States
11-50 Employees
2017
We provide an end-to-end platform for genetic design by integrating state-of-the-art synthetic biology with computational tools. Using our platform, we develop a commercial-grade cell line specifically for your program and ship it to you. We provide you with vials of clonal cell banks, transfer the process to your site, and provide documentation for your regulatory filing. Engineered, highly characterized GMP host cells for therapeutics production with supporting regulatory documentation. We perform cell line development and upstream process development at our site using state-of-the-art equipment and industry-leading timelines. We integrate multiple technologies at the leading edge of synthetic biology, acting as your one-stop shop for cells, genetic tools, computational models, and more. We continuously improve our biological tools, data-driven models, and processes in our state-of-the-art lab in Boston.
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Featured
Home | Asimov — Intelligent Design
... We're integrating mammalian synthetic biology with computer-aided design to advance therapeutic applications. ...
Bengaluru, India
51-100 Employees
2020
We are a value-driven company with a focus on developing environmentally sustainable technologies and solutions. We are experts in fermentation, biocatalysis, and chemical synthesis. We are committed to developing processes with low environmental impact. Zenfold Sustainable Technologies (ZST) is a specialty and fine chemicals manufacturing company committed to sustainable solutions. Established in September 2021, we have headquarters in Bengaluru, India, and facilities in Bengaluru and Hyderabad. We value innovation in everything we do — be it developing new products for our in-house product portfolio or technologies and collaborations. At the intersection of these cutting-edge technologies, lies our unique offerings and value proposition to the pharma sector. Its products and services combine biological synthesis tools with chemistry.
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Featured
Green Chemistry | Biotransformation | Synthetic Biology
... Green Chemistry | Biotransformation | Synthetic Biology ...
Carmel, United States
1-10 Employees
2020
Tom is the Founder of Ramseier Biotech Consulting, Scientific Advisor at Karyosoft, and Adjunct Faculty Member at Ivy Tech Community College.
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Featured
About Us | Ramseier Biotech Consulting
... Expert Biotechnology Solutions Metabolic Engineering Synthetic Biology Technology Due Diligence IP/FTO Analysis Regulatory ...
Zurich, Switzerland
1-10 Employees
Our services help you to make sure pharmaceutical industry, biotech/medtech, and investors will not miss out on novel opportunities We can help you keep track of emerging trends and future therapeutics. We provide you the tools and services that will help your company get noticed. We provide an in-depth analysis of a company's organization, assets, processes, IP, compliance, investigational research and more. Identification and scientific evaluation of break-through, innovative, cutting-edge technologies. We look at product pipeline & portfolio analysis, competitive intelligence, R&D to launch prioritization, ideation & innovation support, product management education. We offer custom packages that fully suit your individual requirements. Use our expertise as a stepping-stone to reach your goals. Applying biology as an engineering discipline for delivering smart therapeutics, lasting cures and new regenerative treatments.
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Featured
Trilliome · Biotechnology, Pharmaceuticals, and Life Sciences Consulting
... Microbiome, Synthetic Biology, Cell Therapy, Gene Therapy, Oncology, Organoids, Body on a Chip, 3D Biology, Digital Health, Consulting, Business Development, ...
Brisbane, United States
11-50 Employees
2019
Recombia was founded in 2019 as a spinout of the Stanford Genome Technology Center. We are now a fully owned subsidiary of Lesaffre. At Recombia Biosciences, our goal is to unlock the full power of biology to make sustainable products. Recombia Bio’s technologies enhance this process, by optimizing yeast through genome editing to address specific industrial manufacturing challenges and bottlenecks. Recombia Biosciences is currently hiring for several openings. In 2023 we expanded to a second location near Boston with a focus on metabolic engineering in a diversity of microorganisms.
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Featured
Recombia Biosciences | Sustainability Through Genome Engineering
... Through Synthetic Biology ...
Synthetic biology is a field of science that involves engineering organisms, such as bacteria, to perform specific functions. It involves the manipulation of existing biological components, such as genes and proteins, to create new living systems or modify existing ones. By combining the principles of engineering with the tools of molecular biology, scientists can design and build biological systems that can produce desirable and valuable products, such as drugs, fuels, and materials. Synthetic biology also has the potential to address global challenges, such as climate change, by providing new solutions and approaches to environmental problems.