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BEOnChip
Zaragoza, Spain
A
1-10 Employees
2016
Key takeaway
Beonchip specializes in "Organ-on-a-Chip" technology, creating microfluidic cell culture devices that replicate the physiological responses of organs in a lab setting. Their innovative approach, combining engineering and biology, allows for advanced in vitro testing that enhances drug, cosmetic, and chemical development.
Reference
Core business
BEOnChip – Biomimetic Environment On Chip | Organ on a Chip technology consists on microfluidic cell culture chips that try to reproduce different physiological responses of organs on a lab. They try to simulate mechanical and chemical stimulations to make the environment as biomimetic as possible.
Fluigent
Le Kremlin-Bicêtre, France
A
11-50 Employees
2005
Key takeaway
Fluigent specializes in advanced fluid control systems for microfluidics, addressing the critical need for precision in applications like organ-on-a-chip research. Their expertise and innovative solutions enhance the performance of fluid handling at the microscale, essential for developing effective organ-on-a-chip technologies.
Reference
Core business
Organ-on-chip - Fluigent
imec
Leuven, Belgium
A
1001-5000 Employees
1982
Key takeaway
The company specializes in organ-on-a-chip technology, which mimics human physiology on silicon to enhance biological models and reduce the need for animal testing. This innovative approach aligns with their commitment to sustainable research and development.
Reference
Service
Organ-on-a-chip technology | imec
By mimicking human physiology on silicon, we improve our biological models without resorting to animal testing.
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React4life
Genoa, Italy
B
1-10 Employees
2016
Key takeaway
MIVO® offers a unique organ-on-a-chip technology that integrates clinically relevant tissue size with independently controlled millifluidic environments, enhancing the study of cell behavior and organ interactions. This innovative platform provides researchers with accurate and physiologically relevant models for investigating complex human diseases.
Reference
Core business
React4Life: Mirroring Human Complexity
MIVO® is the only organ on chip that can combine clinically relevant tissue size with independent millifluidic environments.
Nortis
Woodinville, United States
B
11-50 Employees
2007
Key takeaway
Nortis is a recognized leader in Organ-on-a-Chip (OoC) technology, offering the groundbreaking ParVivo™ System, which features pre-seeded chips containing engineered functional living human tissues. This innovative approach not only allows for the engineering of tissue from a small population of human cells but also simulates the physiological fluidic flow that tissues experience in vivo.
Reference
Product
Products — Nortis
CN Bio Innovations
East Hertfordshire, United Kingdom
A
11-50 Employees
2009
Key takeaway
CN Bio is a pioneering organ-on-a-chip company that specializes in creating innovative PhysioMimix® solutions, enabling the generation of human-specific efficacy and safety data. Their technology allows for the recreation of three-dimensional human organs and tissues in the laboratory, enhancing the understanding of human physiology, disease, and the effectiveness of new drugs.
Reference
Core business
CN Bio | Predictive Organ-on-a-chip Drug Discovery Models
CN Bio is a world leading organ-on-a-chip company. We empower you to transform drug discovery with our predictive human organ models.
Organ-on-a-chip Technologies Network
London, United Kingdom
A
1-10 Employees
-
Key takeaway
The UK Organ-on-a-Chip Technologies Network, established in 2018, brings together scientists, clinicians, and industry professionals to advance organ-on-a-chip technology. The network fosters collaboration and research, highlighting the UK's commitment to expanding this innovative field.
Reference
Core business
The Organ-on-a-Chip Technologies Network
The UK Organ-on-a-Chip Technologies Network was funded by the MRC, EPSRC and BBSRC via the Technology Touching Life initiative, and designed to capture, inspire and grow UK research activity in the Organ-on-a-Chip research field.
Emulate
Boston, United States
B
51-100 Employees
2013
Key takeaway
Emulate specializes in next-generation Organ-on-a-Chip technology that enables researchers to replicate human biology and predict responses to health and disease. Their innovative in vitro models address limitations in traditional research methods, providing valuable tools for exploring complex biological mechanisms.
Reference
Core business
Emulate | Organ-Chips for Research & Development
Next-generation Organ-on-a-Chip technology allows researchers to emulate biology and predict human response. Get started today.
Micronit Microfluidics
Enschede, Netherlands
A
51-100 Employees
1999
Key takeaway
The company specializes in microfluidic product development and manufacturing of lab-on-a-chip consumables, highlighting their expertise in creating innovative diagnostic tests through a comprehensive design-to-manufacturing service.
Reference
Core business
Micronit DE | Micronit | Enabling microfluidic products
River BioMedics
Enschede, Netherlands
A
1-10 Employees
-
Key takeaway
River BioMedics specializes in creating innovative therapies for cardiac diseases by developing 3D cardiac in vitro models, known as "Heart-on-a-Chip." This approach utilizes their expertise in cardiac biology and bio-engineering, particularly with human induced pluripotent stem cells (hiPSC), to enhance drug discovery and development for heart-related conditions.
Reference
Product
Heart-on-a-Chip – River Biomedics
Technologies which have been searched by others and may be interesting for you:
Organ-on-a-Chip refers to a cutting-edge technology that mimics the physiological environment of human organs using microfluidic systems. These systems integrate living cells into a small device, allowing researchers to study organ functionality, disease progression, and drug responses in a controlled setting. By replicating the mechanical and biochemical dynamics of real organs, Organ-on-a-Chip platforms provide valuable insights that can enhance drug development and personalized medicine. They offer a promising alternative to traditional animal testing, enabling more accurate predictions of human reactions to various treatments.
Organ-on-a-Chip technology mimics the functions of human organs using microfluidic systems. These chips contain living cells that represent specific organ tissues, allowing researchers to study biological processes in a controlled environment. By creating tiny channels that simulate blood flow, the technology enables the observation of cellular interactions, drug responses, and disease mechanisms. The chips are designed to replicate the microenvironment of the organs, including factors such as mechanical forces and biochemical gradients. This approach allows for more accurate modeling of human physiology compared to traditional cell culture methods, ultimately leading to improved drug development and disease research.
Organ-on-a-Chip technology serves as a vital tool in medical research, offering numerous applications that enhance our understanding of human biology and disease. This innovative approach enables researchers to create miniature, functional replicas of human organs, allowing for more accurate simulations of physiological responses and disease processes. One significant application is in drug development, where Organ-on-a-Chip models can predict human reactions to new pharmaceuticals, thereby reducing reliance on animal testing. Additionally, these systems facilitate personalized medicine by enabling the study of individual patient responses to therapies. Furthermore, Organ-on-a-Chip platforms are instrumental in understanding disease mechanisms, particularly in areas such as cancer, cardiovascular diseases, and infectious diseases, providing insights that traditional models may not offer.
1. Enhanced Predictive Accuracy
Organ-on-a-Chip technology mimics human organ functions more precisely than traditional methods, allowing for better predictions of drug responses and toxicity. This leads to more reliable data that can be used in early drug development stages.
2. Reduced Animal Testing
By providing a more accurate representation of human biology, Organ-on-a-Chip can significantly decrease the reliance on animal testing. This shift not only adheres to ethical considerations but also improves the relevance of preclinical results to human health outcomes.
3. Cost and Time Efficiency
These systems can streamline research processes, resulting in reduced costs and shorter timelines for drug development. The ability to conduct multiple experiments simultaneously on a single platform enhances productivity and accelerates scientific progress.
4. Personalized Medicine
Organ-on-a-Chip platforms can be tailored to individual patient profiles, offering a pathway to personalized medicine. This customization allows researchers to study disease mechanisms and treatment responses unique to specific genetic backgrounds, leading to more effective therapeutic strategies.
The development of Organ-on-a-Chip technology faces several significant challenges. One major hurdle is the complexity of accurately mimicking the intricate architecture and functions of human organs. Achieving the right cellular interactions and microenvironment is critical for the reliability of these systems. Additionally, scaling up production while maintaining quality and reproducibility poses another challenge. Manufacturers must ensure that the chips can be produced consistently, which often requires sophisticated fabrication techniques. Regulatory hurdles also exist, as the integration of these advanced models into existing drug testing and disease modeling frameworks needs thorough validation to gain acceptance in the scientific and medical communities.
Some interesting numbers and facts about your company results for Organ-on-a-Chip
| Country with most fitting companies | United States |
| Amount of fitting manufacturers | 9394 |
| Amount of suitable service providers | 6393 |
| Average amount of employees | 11-50 |
| Oldest suiting company | 1982 |
| Youngest suiting company | 2016 |
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Some interesting questions that has been asked about the results you have just received for Organ-on-a-Chip
What are related technologies to Organ-on-a-Chip?
Based on our calculations related technologies to Organ-on-a-Chip are Biomedical (Red), Bioinformatics (Gold), Environmental Biotechnology (Grey), Agricultural Biotechnology (Green), Food Related Biotechnology (Yellow)
Which industries are mostly working on Organ-on-a-Chip?
The most represented industries which are working in Organ-on-a-Chip are Biotechnology, Other, Medical, IT, Software and Services, Electronics and Electrical engineering
How does ensun find these Organ-on-a-Chip Companies?
ensun uses an advanced search and ranking system capable of sifting through millions of companies and hundreds of millions of products and services to identify suitable matches. This is achieved by leveraging cutting-edge technologies, including Artificial Intelligence.
