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SeSaM-Biotech GmbH
Germany
A
1-10 Employees
2008
Key takeaway
SeSaM-Biotech specializes in Directed Enzyme Evolution, offering innovative solutions for enzyme engineering through mutagenesis, assay development, and computational design. Their expertise enables clients to enhance enzyme properties, ensuring high-quality enzyme solutions for various applications.
Highlighted product
Core business
Enzyme Evolution | A competitive edge for your enzymes - SeSaM-Biotech
SeSaM-Biotech provides enzyme services in form of Directed Enzyme Evolution, also known as Protein Engineering. Find out more about our specific services.
Enzymaster Deutschland GmbH
Dusseldorf, Germany
A
1-10 Employees
2018
Key takeaway
Enzymaster is a company that specializes in enzyme engineering, with a team of scientists experienced in developing and commercializing enzymes for the production of various chemicals and compounds. Their expertise includes enzyme directed evolution, strain engineering, and biocatalytic production, providing innovative solutions for the fine chemical and pharmaceutical industries.
Highlighted product
Product
Our Technology | enzymaster.de
We offer innovative and sustainable all-round solutions for enyzme catalysis! With our extensive experience in enzyme directed evolution, strain engineering, fermentation process development and commercial scale biocatalytic production, we offer research & development services and product manufacturing to fine chemical, pharmaceutical, and many other industries.
evocatal
Monheim, Germany
A
11-50 Employees
2006
Key takeaway
The AETL Group has enhanced its R&D capabilities through the acquisition of evoxx technologies GmbH, specializing in "Directed Evolution" and "Metagenome" technologies for creating customized enzyme molecules. As the largest Indian enzyme company, AETL focuses on the production and development of over 400 proprietary enzyme products, leveraging its expertise in fermented enzymes manufacturing.
Highlighted product
Service
Enzyme Development – evoxx technologies GmbH
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EnginZyme
Stockholm, Sweden
A
1-10 Employees
2014
Key takeaway
EnginZyme is a Swedish startup focused on transforming the chemical industry by harnessing the potential of enzymes through their innovative cell-free biomanufacturing platform. Their approach allows for the use of enzymes as catalysts in a more efficient and environmentally friendly manner, promising to reduce reliance on traditional chemicals.
Highlighted product
Product
EnginZyme platform – EnginZyme
Gecco Biotech B.V.
Groningen, Netherlands
A
1-10 Employees
-
Key takeaway
Gecco Biotech specializes in sustainable enzymatic solutions across various fields, including chemistry and pharmaceuticals. They offer a comprehensive range of services from enzyme discovery and engineering to downstream processing, ensuring tailored products that enhance enzyme stability, specificity, and activity.
Highlighted product
Core business
Home - Gecco Biotech
Enantis
Brno, Czechia
A
11-50 Employees
2006
Key takeaway
Enantis is a biotech company that specializes in protein and enzyme engineering, utilizing its proprietary platform to address complex challenges. They offer services in protein engineering and are developing thermostable fibroblast growth factors, highlighting their expertise in this field.
Highlighted product
Service
Services - Enantis
Advanced Enzymes
Thane, India
D
251-500 Employees
1989
Key takeaway
Advanced Enzymes is a leading Indian enzyme company that focuses on the research, development, and manufacturing of over 400 proprietary enzyme products. With a strong commitment to eco-safe solutions, the company is at the forefront of enzyme innovation, providing tailored enzyme applications across diverse industries such as healthcare, nutrition, textiles, and more.
Highlighted product
Service
Services Archive - Advanced Enzymes
Supa Hot Crew
Germany
A
1-10 Employees
2013
Key takeaway
Enzyme.bio is dedicated to the development of high-quality enzyme products, emphasizing their reliability and ease of use for bio firms and labs. Their offerings include a range of diagnostic and food-grade enzymes, showcasing their commitment to advancing enzyme technology.
Highlighted product
Core business
Home - enzymes.bio
We are enzyme.bio, a team of scientists who are passionate about enzymes. We believe in their power to make a difference in the world, and we’re committed to
EUCODIS Bioscience
Vienna, Austria
A
11-50 Employees
2007
Key takeaway
Biosynth specializes in enzyme engineering, offering high-performance enzyme solutions for various industries, including pharma and biotech. With a portfolio of over 50 enzymes and expertise in customizing biocatalysts, they utilize proprietary technologies to optimize enzyme activities and meet specific customer needs.
Highlighted product
Service
EUCODIS Bioscience | Services
Custom Enzymes
Adelaide, Australia
A
11-50 Employees
2020
Key takeaway
Custom Enzymes is a leading global supplier of innovative custom enzymatic formulations, specializing in developing organic enzyme alternatives for various applications. Their advanced biostimulant products aim to enhance efficiencies and improve business outcomes.
Highlighted product
Product
Products | Custom Enzymes
https://www.customenzymes.com/Products There is an enzyme alternative for almost every process that uses harsh persistent chemicals in the world. At Custom Enzymes we specialise in developing and innovating using completely organic ingredients.
Technologies which have been searched by others and may be interesting for you:
Enzyme engineering involves the design and modification of enzymes to enhance their properties and functionalities for various applications. This process utilizes techniques such as directed evolution and rational design to create enzymes that can withstand extreme conditions or catalyze specific reactions more efficiently. The field plays a significant role in industries like pharmaceuticals, biofuels, and food processing, where tailored enzymes can improve production rates and reduce environmental impact. By optimizing enzyme performance, businesses can achieve cost-effectiveness and sustainability in their processes.
Enzyme engineering significantly enhances the biotechnology industry by optimizing enzyme functions for specific applications. This process allows for the development of enzymes with improved stability, activity, and specificity, which can lead to more efficient biocatalysis in various industrial processes. Additionally, tailored enzymes can increase the yield of desired products while minimizing by-products, thereby reducing waste and lowering costs. In fields such as pharmaceuticals, agriculture, and biofuels, engineered enzymes contribute to innovative solutions that improve product quality and sustainability.
1. Directed Evolution
This technique mimics natural selection to evolve proteins or enzymes toward a user-defined goal. By introducing mutations at specific sites and screening for desired traits, researchers can significantly enhance enzyme performance.
2. Rational Design
Rational design involves the use of structural information about enzymes to make informed modifications. By analyzing the enzyme's active site and overall structure, scientists can predict how changes will affect function and stability.
3. High-Throughput Screening
This method allows for the rapid testing of numerous variants of an enzyme to identify those with improved characteristics. Such techniques enable the efficient identification of lead candidates for further development.
4. Site-Directed Mutagenesis
This approach allows for the precise alteration of specific amino acids in an enzyme's sequence. By targeting specific locations, scientists can study the impact of these changes on enzyme activity and stability.
5. Gene Shuffling
Gene shuffling combines segments of different genes to create a library of enzyme variants. This technique enhances diversity and increases the chances of discovering enzymes with desirable traits.
Challenges in enzyme engineering often stem from the complexity of enzyme structures and their functions. One significant hurdle is stability, as engineered enzymes may not maintain their activity under varying environmental conditions, such as temperature and pH. Additionally, specificity poses a challenge; achieving the desired selectivity for substrates while minimizing off-target effects requires precise modifications, which can be difficult to predict. Another challenge is scalability. While laboratory successes in enzyme engineering may be promising, translating these findings into industrial applications can be complex and costly. Furthermore, regulatory compliance adds another layer of difficulty, as engineered enzymes must meet safety and efficacy standards before commercial use, which can prolong development timelines.
Enzyme engineering plays a crucial role in pharmaceuticals by enhancing the efficiency and specificity of drug production processes. By modifying enzymes at the molecular level, it is possible to create biocatalysts that can facilitate complex chemical reactions under mild conditions. This not only reduces the need for harsh chemicals but also minimizes by-products, leading to a more sustainable manufacturing process. Furthermore, engineered enzymes can improve the bioavailability and therapeutic efficacy of drugs. They can be designed to target specific substrates, ensuring that the active pharmaceutical ingredients are released in a controlled manner. Such precision in enzyme design can lead to better patient outcomes and reduced side effects, making enzyme engineering an essential component in the development of modern pharmaceuticals.
Some interesting numbers and facts about your company results for Enzyme Engineering
| Country with most fitting companies | United Kingdom |
| Amount of fitting manufacturers | 6402 |
| Amount of suitable service providers | 7118 |
| Average amount of employees | 11-50 |
| Oldest suiting company | 1989 |
| Youngest suiting company | 2020 |
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Some interesting questions that has been asked about the results you have just received for Enzyme Engineering
What are related technologies to Enzyme Engineering?
Based on our calculations related technologies to Enzyme Engineering are Biomedical (Red), Bioinformatics (Gold), Environmental Biotechnology (Grey), Agricultural Biotechnology (Green), Food Related Biotechnology (Yellow)
Who are Start-Ups in the field of Enzyme Engineering?
Start-Ups who are working in Enzyme Engineering are Custom Enzymes
Which industries are mostly working on Enzyme Engineering?
The most represented industries which are working in Enzyme Engineering are Biotechnology, Other, Manufacturing, IT, Software and Services, Oil, Energy and Gas
How does ensun find these Enzyme Engineering Companies?
ensun uses an advanced search and ranking system capable of sifting through millions of companies and hundreds of millions of products and services to identify suitable matches. This is achieved by leveraging cutting-edge technologies, including Artificial Intelligence.
