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REGENXBIO
Rockville, United States
B
251-500 Employees
2009
Key takeaway
REGENXBIO is focused on advancing in vivo gene therapy through its innovative AAV gene therapies, aiming to provide one-time treatments for various diseases. Their commitment to research and development in this field highlights their role as pioneers in gene therapy.
Reference
Core business
Pioneers in Gene Therapy
Kriya Therapeutics
Palo Alto, United States
B
51-100 Employees
2019
Key takeaway
The company is focused on developing transformative gene therapies for widespread conditions, aiming to make these treatments accessible to many. Their innovative approaches target validated biological pathways, emphasizing their commitment to advancing the field of gene therapy.
Reference
Core business
Home - Kriya Therapeutics
Gene Therapy. Redefined. We are developing life changing gene therapies for conditions affecting millions of people around the world. Our mission is to make genetic medicines accessible – not just for the few – but for the many. In Sanskrit, Kriya (“kree-yah”) means “action.” When we succeed, Kriya – in every language – will mean […]
Be The Match BioTherapies
Minneapolis, United States
B
1001-5000 Employees
2016
Key takeaway
Be The Match BioTherapies is dedicated to providing comprehensive support for both allogeneic and autologous cell and gene therapy development. With over 35 years of experience, they empower the discovery, development, and delivery of next-generation therapies, ensuring that patients receive the critical treatments they need.
Reference
Product
Cell and Gene Therapy Solutions | Be The Match BioTherapies
Be The Match BioTherapies helps you mitigate risk with allogeneic or autologous cell and gene therapy solutions that scale with you at every step.
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Interius BioTherapeutics
Philadelphia, United States
B
11-50 Employees
2019
Key takeaway
Interius is focused on advancing in vivo gene therapy by developing innovative methods to engineer cells directly within the human body. Their approach involves reengineering viral vectors to enhance the effectiveness of cell-specific therapies, particularly for diseases that current modalities cannot adequately address.
Reference
Core business
Gene Therapy | In Vivo Cell Therapy | In Vivo Gene Therapy | Interius
Interius is a preclinical stage company expanding the potential of gene therapy by reengineering viral vectors to drive cell-specific therapy.
Genezen Laboratories
Indianapolis, United States
B
1-10 Employees
2014
Key takeaway
Genezen is a specialized viral vector contract development and manufacturing organization (CDMO) that focuses on GMP manufacturing of lentiviral and retroviral vectors, which are critical for in vivo gene therapy applications. With a commitment to accelerating the development and commercialization of innovative therapies, Genezen offers extensive expertise and capacity in viral vector process development and manufacturing.
Reference
Core business
Genezen | GMP Viral Vector Manufacturer | Viral Vector CDMO
Genezen is a US-based viral vector CDMO specializing in GMP viral vector manufacturing, viral vector development, cell manufacturing & testing
iECURE
Philadelphia, United States
B
- Employees
2012
Key takeaway
iECURE is dedicated to in vivo gene therapy, specifically focusing on gene editing for liver disorders in children. They are developing innovative approaches to treat conditions like ornithine transcarbamylase deficiency and phenylketonuria, emphasizing the potential of gene editing to address significant patient needs.
Reference
Core business
Home | iECURE
Knocking down devastation. Inserting hope. At iECURE, we believe in vivo gene editing is the answer to meeting this immense patient need, and we believe reversing the course of these conditions is now within reach.
Expression Therapeutics
Tucker, United States
B
11-50 Employees
-
Key takeaway
Expression Therapeutics specializes in developing gene therapies for various conditions, including Hemophilia A and B, Neuroblastoma, and leukemia. Their advanced manufacturing facility supports the production of cGMP LV and AAV vectors, enhancing the development of their clinical programs.
Reference
Core business
Expression Therapeutics
Affinia Therapeutics
Waltham, United States
B
51-100 Employees
2019
Key takeaway
Affinia Therapeutics is dedicated to advancing in vivo gene therapy by addressing the limitations of conventional AAV capsids and employing innovative design and manufacturing approaches. Their platform enhances tissue targeting and cell expression, expanding the potential of gene therapies to treat a variety of diseases effectively.
Reference
Core business
Affinia Therapeutics - Adeno Associated Virus (AAV) Gene Therapy
Aldevron
Fargo, United States
B
101-250 Employees
1998
Key takeaway
Aldevron has extensive experience in advancing therapeutic development, providing high-quality plasmid DNA and other biologicals essential for in vivo gene therapy. Their focus on non-viral approaches and scalable mRNA manufacturing highlights their commitment to improving performance and safety in modern therapeutic applications.
Reference
Product
Reviver and HyperGro
American Gene Technologies International
Rockville, United States
B
11-50 Employees
2007
Key takeaway
American Gene Technologies is dedicated to developing gene and cell therapies, particularly for monogenic disorders and cancers. Their innovative approach includes a Phase 1 trial of AGT103-T, a modified T cell therapy that offers promise for a functional cure for HIV.
Reference
Core business
Addimmune: Advancing a Cure for HIV Through Gene Therapy
Imagine a world without HIV. Addimmune's gene therapy technology is helping make that a reality.
Technologies which have been searched by others and may be interesting for you:
When exploring the in vivo gene therapy industry in the United States, several key considerations come into play. Regulatory compliance is paramount, as the Food and Drug Administration (FDA) oversees the approval processes for gene therapies. Companies must navigate complex clinical trial phases while adhering to stringent safety and efficacy requirements. The competitive landscape is rapidly evolving, with numerous biotech firms and research institutions developing innovative therapies, thus presenting both opportunities and challenges. Funding is another critical factor; significant investment is often required for research and development, and partnerships with pharmaceutical companies can provide necessary resources. Additionally, it's essential to stay informed about the latest scientific advancements and technological innovations that drive this field. Environmental concerns, particularly regarding the long-term effects of gene therapies, are increasingly relevant, prompting discussions about ethical implications and ecological impacts. The global market for gene therapy is expanding, with the U.S. being a leader in this sector. Understanding the international regulatory environment and market dynamics can provide insights into potential collaborations or competition. Overall, thorough research into these factors will help individuals and organizations make informed decisions in the in vivo gene therapy landscape.
Some interesting numbers and facts about your company results for In Vivo Gene Therapy
| Country with most fitting companies | United States |
| Amount of fitting manufacturers | 3312 |
| Amount of suitable service providers | 2041 |
| Average amount of employees | 51-100 |
| Oldest suiting company | 1998 |
| Youngest suiting company | 2019 |
Some interesting questions that has been asked about the results you have just received for In Vivo Gene Therapy
What are related technologies to In Vivo Gene Therapy?
Based on our calculations related technologies to In Vivo Gene Therapy are Biomedical (Red), Bioinformatics (Gold), Environmental Biotechnology (Grey), Agricultural Biotechnology (Green), Food Related Biotechnology (Yellow)
Which industries are mostly working on In Vivo Gene Therapy?
The most represented industries which are working in In Vivo Gene Therapy are Biotechnology, Other, Medical, Healthcare, Pharmaceuticals
How does ensun find these In Vivo Gene Therapy Companies?
ensun uses an advanced search and ranking system capable of sifting through millions of companies and hundreds of millions of products and services to identify suitable matches. This is achieved by leveraging cutting-edge technologies, including Artificial Intelligence.
