Oncolytic Virus
Oncolytic Virus
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Top Oncolytic Virus Companies

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24 companies for Oncolytic Virus

Imanis Life Sciences's Logo

Rochester, United States

1-10 Employees

2012

Our mission is to accelerate development of novel therapeutics by providing researchers with high-quality products and services for all stages of research. We are passionate about diving deep into the science to discover novel and innovative solutions for next-generation therapies. We are all about working with sponsors to help them overcome the challenges of their research. We provide a wide range of services to support early research and development through the clinical phase. We provide custom biodistribution, immunogenicity, pharmacokinetics, and biomarker assay services to support discovery through clinical phases. Experts in virology, immuno-oncology, cell and vector engineering, and assay development, our vision is to be a leader in research services and laboratory assays. This scientific approach to each project is what allows us to deliver excellence in contract research, custom products, and virus assays to support development of oncolytic virus therapies, gene and cell therapies, regenerative medicines, and vaccines. What makes Imanis stand out is our diverse scientific team of experts in virology, immuno-oncology, molecular biology, and assay development.

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Product
Image for HSV-GFP Reporter Gene Oncolytic Virus - Imanis Life Sciences

HSV-GFP Reporter Gene Oncolytic Virus - Imanis Life Sciences

... Explore the description, propagation, and transgene validation for the HSV-GFP reporter gene oncolytic virus from Imanis Life Sciences. ...

Creative Biogene's Logo

Our mission is to deliver the highest quality products, to provide dedicated technical support to our customers worldwide, and to satisfy customers' specific needs with customized solutions. We are fully engaged in developing unique technologies to facilitate the investigation of microbial research. Our promise to you: Guaranteed product quality, expert customer support. As a scientists-founded and scientists-driven leading biotechnological company, Creative Biogene focuses on developing high quality products and services, as well as proprietary technology to support the research in the field of basic life sciences research, biomedical development, industrial synthetic application and preclinical drug discovery. With the support of an innovative portfolio of products and a custom-service-centered business model, Creative Biogene is gradually recognized by worldwide customers as a biotech institution specializing in fundamental life sciences research. At Creative Biogene, Our in-house experts continually work on developing tools and innovative solutions for the bioresearch community. Creative Biogene provides customized molecular biology reagents and professional technical services to customers in the life science research field. Kit is a collection of reagents or devices that can perform a specific biological experiment.

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Product
Image for Oncolytic Virus

Oncolytic Virus

... Oncolytic Virus - Creative ...

CanVirex's Logo

Basel, Switzerland

1-10 Employees

2017

Our vision: Affordable, best-in-class cancer treatments with fewer side effects for an improved quality-of-life under treatment. CanVirex is a spin-off from the Heidelberg University Hospital, founded in 2017 in Basel, Switzerland. CanVirex and Heidelberg University Hospital have signed a strategic collaboration agreement for the research and clinical development of measles-vectored therapeutics. CanVirex has also forged strategic collaborations with key industry partners for GMP manufacturing and commercialization of our products. CanVirex’s measles vector-based platform represents a highly promising technology for cancer immunotherapy and vaccine development against infectious diseases. CanVirex AG operates out of its headquarter in Basel, Switzerland. The Heidelberg University Hospital offers a unique infrastructure for swift clinical translation of our most promising drug candidates. The translational program, supported by CanVirex, routinizes testing of molecular signatures and predictive biomarkers.

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Core business
Image for CanVirex – Targeted oncolytic immunomodulation breaking tumor resistance

CanVirex – Targeted oncolytic immunomodulation breaking tumor resistance

... Oncolytic measles virus-vectored platform for cancer ...

Open Therapeutics's Logo

Cincinnati, United States

1-10 Employees

2009

Therapoid' free Therapoid open science platform enables responsible and socioeconomically diverse researchers and students around the world to collaborate. All the sciences impact animal, human, and global health outcomes. This includes the impacts brought about by climate change. Our interdisciplinary approach supports achieving positive health outcomes for everyone. Therapoid enables scientists and students to share research easily, while it also opens a path to develop untapped technologies.

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Featured

Product
Image for oncolytic herpes simplex virus (oHSV)-Gluc for cancer screening

oncolytic herpes simplex virus (oHSV)-Gluc for cancer screening

... Summary | oncolytic herpes simplex virus (oHSV)-Gluc for cancer screening | ...

Tessa Therapeutics's Logo

singapore, Singapore

101-250 Employees

2001

Tessa Therapeutics is a clinical-stage biotechnology company developing a portfolio of novel next-generation cell therapies for cancer. Off-the-shelf allogeneic cell therapy has significant advantages and is the next frontier in cancer treatment. Tessa is developing a unique and potentially transformational allogeneic CD30-CAR EBVST platform capable of targeting a broad range of cancers. This platform is based on decades-long research and development on unique properties of Virus Specific T-cells (VSTs) by our Scientific Co-Founder, Dr. Malcolm Brenner, and his team at Baylor College of Medicine.

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Product
Image for Technology | Tessa Therapeutics – Cancer Immunotherapy Treatments

Technology | Tessa Therapeutics – Cancer Immunotherapy Treatments

... Oncolytic Virus ...

Rigvir Holding's Logo

Riga, Latvia

101-250 Employees

2003

The story of Rigvir Group was started by professor Aina Muceniece, a pioneer scientist who looked into the future and unlocked the potential of oncolytic virotherapy for cancer patients. Rigvir Group wishes success and rapid expansion of the good virus around the world. Rigvir has once again received international confirmation that it is non-toxic, has high tolerability and does not induce any severe adverse event even at increased doses. Henceforth, Rigvir virus is going to be developed also in the non-medical field which could provide preventive help to people with high cancer-risks or scientifically proven cancer presence in the body even before cancer can be diagnosed. Rigvir group has made a decision to offer a fundamentally new approach to cancer prevention. With this deal, the Rigvir group has further distanced itself from the commercialisation of the medicine and approached Biotech format with a focus on product development and further licensing. Rigvir's new API (Active pharmaceutical ingredient) center of manufacturing has received GMP (Good Manufacturing Practice) compliance certification for the production of Rigvir virus ECHO-7. We are committed to prove, that the cancer treatment can be safe, effective and harmless.

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Image for Biotech Company - Rigvir Group

Biotech Company - Rigvir Group

... The core elements of the organization strategy are the production of the unique oncolytic virus ECHO-7 virus. ...

ABL's Logo

Illkirch-Graffenstaden, France

51-100 Employees

2016

We are a pure play Contract Development and Manufacturing Organization (CDMO) specialized in the development and manufacturing of gene therapies, oncolytic viruses and vaccine candidates. Our mission is to provide GMP viral vectors from early-stage to market, contributing to the success of our clients’ immunotherapy and gene therapy innovations. We are grounded in the Mérieux family’s legacy of biology and vaccine expertise, dating back to 1897. More than ever, our vision is to contribute to a long-term public health vision where Bio-Industry has a central role for a healthier world. OUR MISSION: By accelerating our Customer’s life-saving innovations, ABL is contributing to a long-term public health vision where Bio-Industry has a central role for a healthier world. OUR VISION: Become a leading global biomanufacturing CDMO trusted to deliver innovation and excellence. We produce a wide range of viral vectors: Vaccinia, MVA, Adeno, Measles, ORF, Arenavirus, AAV and others. We are grounded in the Mérieux family’s legacy of biology and vaccine expertise since 1897.

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Core business
Image for ABL Biomanufacturing - GMP manufacturing of viral vectors

ABL Biomanufacturing - GMP manufacturing of viral vectors

... ABL AND IMUGENE PARTNER TO ADVANCE ONCOLYTIC VIRUS CANDIDATE TOWARDS LATER PHASE CLINICAL ...

Nitta Gelatin USA's Logo

Morrisville, United States

101-250 Employees

1979

Through an unwavering dedication to customer service and emphasis on innovative technologies, Nitta Gelatin has expanded its footprint, with 15 facilities across 6 countries. Utilizing our technical expertise and over a century of know-how, we provide our customers with leading-edge R&D, exceptional technical service, and consistently high-quality products. In 2006, Nitta Gelatin opened the doors to its state-of-the-art gelatin and collagen peptide production facility in Fayetteville, North Carolina. Nitta Gelatin celebrates over 100 years as a trusted producer of gelatin and collagen ingredients for the food, dietary supplement, and pharmaceutical markets. Founded in Osaka, Japan, Nitta gelatin has grown into a global supplier, with 15 facilities across 6 countries. In keeping with our pioneering spirit, Nitta Gelatin continually strives to develop new products, functions, and applications for the future. Rapid-set gelatin designed for use with complex formulations and starchless gummy manufacturing. Exceptionally high biocompatibility, viral inactivation, and endotoxin reduction, yielding collagen and gelatin products for the biomedical marketplace.

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Core business
Image for Home BeMatrix | Nitta Gelatin

Home BeMatrix | Nitta Gelatin

... Example (Oncolytic Virus) ...

Virogin Biotech's Logo

Vancouver, Canada

11-50 Employees

2015

Our vision is to be a global, best-in-class immuno-oncology company that creates impactful drugs for patients with the highest medical needs. Founded in Canada in 2015, Virogin aims to unleash synergy between oncolytic virotherapy and mRNA vaccines in the battle against cancer. We have developed two platforms: (1) innovative HSV-1 based oncolytic virus and (2) mRNA-based (including self-amplifying RNA/saRNA) therapeutics, aiming to elicit robust and durable anti-tumor immune response against solid tumors.

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Core business
Image for About - Virogin

About - Virogin

... About Us Virogin Biotech was founded in Canada in 2015, with a vision to be a global, best-in-class oncolytic virus company that creates impactful drugs for patients with the highest medical need. We have over 170 employees, with R&D facilities in Canada and China. At Virogin, we are at the ...

WuXi Discovery Services's Logo

Panyu District, China

10001+ Employees

2000

Through comprehensive discovery and technology platforms, peer-recognized scientific leadership and expertise in oncology, immunology, infectious disease, neurosciences, fibrosis, cardiovascular and metabolic disease, we work collaboratively to rapidly advance programs from target through to preclinical selection and beyond. This integration of capabilities allows a collaborative environment, enabling enhanced efficiency and productivity. We aim to provide outstanding services to our existing partners and to the broader discovery community. Delivering our partners preclinical discoveries through world class capabilities, directed by teams with a reputation for collaboration and scientific excellence. WuXi Biology provides a full spectrum of services and solutions to support stand-alone and integrated projects, from target discovery to candidate selection and into the clinic. Our world-class discovery platform is backed by nearly 3000 scientists, offering expertise in all major disease areas and target classes, across all therapeutic modalities. From small molecules, oligonucleotides, and peptides to antibodies, cell, and gene therapies, our state-of-the-art services, fast turnaround times, and quick study launches meet the diverse needs of our clients. Expertise in synthetic and medicinal chemistry, biology, DMPK and program management for drug discovery.

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Featured

Product
Image for Oncolytic Viruses - WuXi Biology

Oncolytic Viruses - WuXi Biology

... Offering a comprehensive platform of oncolytic virus-related services, including lysis activity, cytokine assessment, efficacy testing & safety assays. ...


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Facts about those Oncolytic Virus Results

Some interesting numbers and facts about the results you have just received for Oncolytic Virus

Country with most fitting companiesUnited States
Amount of fitting manufacturers20
Amount of suitable service providers13
Average amount of employees101-250
Oldest suiting company1979
Youngest suiting company2017

Geographic distribution of results





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Things to know about Oncolytic Virus

What is Oncolytic Virus?

An oncolytic virus refers to a genetically engineered or naturally occurring virus that selectively infects and destroys cancer cells without causing significant damage to normal tissue. By exploiting the unique vulnerabilities of cancer cells, such as their rapid division rates and compromised antiviral defenses, oncolytic viruses are designed to replicate within these malignant cells, ultimately leading to cell lysis or apoptosis. This process not only directly reduces tumor mass but also stimulates the host's immune system to recognize and attack cancer cells, thereby providing a dual mechanism of action against the disease. The therapeutic application of oncolytic viruses represents a significant advancement in oncology, offering a novel approach that complements traditional cancer treatments, such as chemotherapy, radiation, and surgery. Their capacity to specifically target cancer cells, while minimizing harm to healthy cells, addresses a critical challenge in cancer therapy, potentially reducing the side effects associated with conventional treatments. Furthermore, the ability of oncolytic viruses to induce a systemic immune response against tumors provides an innovative strategy for combating metastatic cancer, which remains a leading cause of cancer-related death. As research progresses, the development of oncolytic virotherapy continues to show promise, broadening the horizons of cancer treatment and offering hope for more effective and less toxic therapeutic options.


Advantages of Oncolytic Virus

1. Targeted Therapy:
Oncolytic viruses are designed to selectively infect and kill cancer cells without harming normal cells. This specificity reduces the risk of damage to healthy tissues, a significant advantage over traditional treatments like chemotherapy, which can harm both cancerous and healthy cells.

2. Stimulating Immune Response:
Unlike many other treatments, oncolytic viruses can provoke a potent immune response against the tumor. They do this by exposing the tumor's antigens to the immune system in a way that is more recognizable, effectively turning the cancer into a target for the body's natural defenses.

3. Reduced Side Effects:
Due to their targeted approach and the natural way they work with the body's immune system, oncolytic viruses often have fewer and less severe side effects compared to conventional cancer treatments. This can significantly improve the quality of life for patients undergoing cancer therapy.

4. Combination Therapy Potential:
Oncolytic viruses can be combined with other cancer treatments, such as chemotherapy or radiation, to enhance their effectiveness. This synergistic effect can lead to better outcomes for patients, including reduced tumor size and slower disease progression.


How to select right Oncolytic Virus supplier?

While evaluating the different suppliers make sure to check the following criteria:

1. Quality Assurance and Certifications
Ensure the supplier has rigorous quality control processes and relevant certifications (e.g., GMP, ISO) that guarantee the oncolytic viruses meet the highest standards for clinical research and therapeutic use.

2. Virus Strain Variety
Check the variety of oncolytic virus strains the supplier offers. A broad selection allows for more tailored research and treatment approaches.

3. Customization Capabilities
Assess the supplier's ability to customize viral vectors according to specific therapeutic needs, including genetic modifications and targeting specificities.

4. Safety and Efficacy Data
Look for comprehensive safety and efficacy data supporting the use of their oncolytic viruses in preclinical models and, if available, in clinical settings.

5. Technical Support
The supplier should offer robust technical support, including consultation on virus selection, use, and troubleshooting, to ensure successful application.

6. Delivery and Packaging
Verify that the supplier can provide secure, temperature-controlled shipping and appropriate packaging to maintain virus viability during transport.

7. Cost-effectiveness
While not compromising on quality, consider the cost-effectiveness of the supplier's offerings to ensure it aligns with your budget and research funding.


What are common B2B Use-Cases for Oncolytic Virus?

Oncolytic viruses, a groundbreaking approach in cancer therapy, leverage genetically modified viruses to infect and kill cancer cells while sparing healthy ones. This innovative treatment has paved the way for various B2B use cases across different industries. In the pharmaceutical and biotechnology sectors, collaboration on research and development is a significant use case. Companies specializing in oncolytic virus therapy join forces with larger pharmaceutical entities to accelerate the development, clinical trials, and eventual commercialization of these treatments. This partnership allows for the sharing of resources, expertise, and financial risks, expediting the process of bringing new therapies to market. The healthcare and clinical services industry presents another use case, focusing on the customization of oncolytic virus therapies for specific patient groups. Healthcare providers partner with biotech firms to offer personalized medicine solutions, tailoring treatments to the genetic makeup of an individual's cancer. This collaboration enhances treatment efficacy and patient outcomes, marking a shift towards more personalized healthcare services. Lastly, in the medical equipment and diagnostics field, companies are developing advanced diagnostic tools to identify patients most likely to benefit from oncolytic virus therapy. By collaborating with biotech firms, these companies are creating precision diagnostic equipment that can detect specific biomarkers indicating a patient's compatibility with oncolytic virus treatments, thus optimizing therapeutic outcomes. These use cases underscore the interdisciplinary collaboration between biotech, pharmaceutical, healthcare, and diagnostic industries, all aimed at harnessing the full potential of oncolytic viruses to revolutionize cancer treatment.


Current Technology Readiness Level (TLR) of Oncolytic Virus

As of my last update in 2023, oncolytic viruses (OVs) occupy a Technology Readiness Level (TRL) that can be broadly classified between TRL 6 to TRL 8, depending on the specific virus and its application. This positioning is due to several pivotal factors associated with the development, testing, and approval stages that these therapeutic agents have undergone. At this stage, oncolytic viruses have demonstrated considerable efficacy in controlled environments (TRL 6), with some having progressed to demonstration in relevant environments through clinical trials (TRL 7). A few have reached TRL 8, where they have proven their effectiveness and safety in actual healthcare settings, leading to regulatory approval for public use. The technical reasons underpinning their placement within these levels include the successful engineering of viruses to selectively infect and kill cancer cells while sparing healthy cells, the ability to manufacture these biological agents at a scale that is both efficient and meets regulatory standards, and the accumulation of clinical data that supports their safety and efficacy. Furthermore, the refinement of delivery methods to target tumors more effectively, and the ongoing development of strategies to circumvent the immune system's response to these viruses, also play crucial roles in advancing their TRL. The variability in TRL across different oncolytic viruses underscores the diversity in their mechanisms of action, targets, and stages of development and deployment in the fight against cancer.


What is the Technology Forecast of Oncolytic Virus?

In the short term, advancements in oncolytic virus technology are expected to focus on enhancing virus specificity and safety. The next few years will likely see the development of more targeted oncolytic viruses that can selectively infect and kill cancer cells while minimizing damage to healthy cells. This period will also witness improvements in delivery mechanisms, ensuring that these therapeutic viruses can efficiently reach and infiltrate tumors, even those that are deeply embedded or difficult to access. In the mid-term, the emphasis will shift towards combination therapies and personalized medicine. Oncolytic viruses will be engineered to work synergistically with other cancer treatments, such as chemotherapy, radiation, and immunotherapy, to improve patient outcomes. This phase will also explore the customization of oncolytic viruses to individual patients' genetic profiles, enhancing treatment efficacy and reducing side effects. Additionally, we can expect the development of oncolytic viruses capable of evading the immune system, allowing for prolonged and effective engagement with cancer cells. Long-term developments will likely revolutionize cancer treatment through the integration of cutting-edge technologies like CRISPR for gene editing and artificial intelligence for predictive analytics. These tools will enable the creation of highly sophisticated oncolytic viruses that can be dynamically programmed to adapt to the evolving landscape of a tumor, potentially offering a cure for cancer. The long-term vision includes the establishment of oncolytic viruses as a standard, non-invasive treatment option for various cancer types, significantly reducing the global cancer burden.


Frequently asked questions (FAQ) about Oncolytic Virus Companies

Some interesting questions that has been asked about the results you have just received for Oncolytic Virus

Based on our calculations related technologies to Oncolytic Virus are Biomedical (Red), Bioinformatics (Gold), Environmental Biotechnology (Grey), Agricultural Biotechnology (Green), Food Related Biotechnology (Yellow)

The most represented industries which are working in Oncolytic Virus are Biotechnology, Health Care, Science and Engineering, Professional Services, Administrative Services

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