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ADARx Pharmaceuticals
San Diego, United States
B
11-50 Employees
2019
Key takeaway
ADARx Pharmaceuticals is focused on developing an innovative RNA targeting platform, which includes RNA editing that specifically targets and precisely edits RNA sequences. This approach is part of their mission to create transformative therapeutics for intractable diseases.
Reference
Service
RNA Editing | ADARx Pharmaceuticals
ADARx Pharmaceuticals through the RNA editing approach specifically targets an RNA sequence and precisely edits a single base. Learn more here!
Korro Bio
Cambridge, United States
B
51-100 Employees
2018
Key takeaway
Korro Bio is at the forefront of RNA editing, highlighting its potential to transform the future of medicine.
Reference
Core business
Korro Bio – Edit the message. Rewrite the future.
FLUOROGENICS LIMITED
Salisbury, United Kingdom
A
1-10 Employees
2011
Key takeaway
The company offers the NEBNext UltraExpressâ„¢ RNA Library Prep Kit, which enables the rapid creation of high-quality directional RNA libraries. This kit can be effectively paired with poly(A) mRNA enrichment or rRNA depletion kits, addressing challenges in mRNA manufacturing and scale-up.
Reference
Product
RNA Modification | NEB
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LabOmics
Nivelles, Belgium
A
1-10 Employees
2008
Key takeaway
The company, LabOmics, specializes in vector-based expression and offers a range of tools for genome editing, including RNP Editing Tools and CRISPR technologies. Their collection of promoter reporter clones and antibodies may also support research related to RNA editing and gene regulation.
Reference
Product
RNP - RGENs- CRISPRs - CRISPR-RGEN, TALEN & ZFN - Products
Eclipse Bioinnovations
San Diego, United States
B
11-50 Employees
2017
Key takeaway
Eclipsebio is a biotechnology company focused on advancing RNA genomics through innovative technologies and Next Generation Sequencing (NGS). Their comprehensive RNA genomics platform supports researchers in developing new RNA therapeutics and enhancing understanding of RNA beyond traditional RNA-Seq methods.
Reference
Core business
Eclipse Bioinnovations | Robust RNA Genomics Solutions
Previous slide Next slide Eclipsebio offers RNA genomics solutions with Next Generation Sequencing technologies to accelerate the development of
Eupheria Biotech GmbH
Dresden, Germany
A
1-10 Employees
-
Key takeaway
Eupheria Biotech GmbH specializes in RNA interference (RNAi) and offers endoribonuclease-prepared siRNAs and in-vitro transcribed single-stranded RNA sequences, which are essential for targeting specific genes and studying host-virus interactions, particularly related to SARS-CoV-2. Their innovative products, including esiRNAs and the esiCRISPR line, facilitate advanced research in RNA editing and genome engineering.
Reference
Product
iB-RNA libraries - Eupheria Biotech
BIOEDIT LIMITED
United Kingdom
A
1-10 Employees
-
Key takeaway
Bioedit specializes in providing expert English editing services for researchers in the medical and life sciences, helping to enhance the clarity and impact of their manuscripts. With over two decades of experience, Bioedit has established itself as a trusted partner for authors looking to publish their findings in top journals.
Reference
Core business
English editing for scientific research manuscripts | Bioedit
Biolegio
Nijmegen, Netherlands
A
11-50 Employees
1996
Key takeaway
Biolegio specializes in custom oligonucleotide synthesis, providing primers and probes for applications like RT-qPCR, which is crucial for RNA editing and related research. With over 20 years of experience, they support global customers in making significant discoveries in the life sciences.
Reference
Product
Advanced RNA | Biolegio
Biolegio priovides custom oligos for the life science market. Offering primers, probes for qPCR at competitive pricing with excellent service....
Northern RNA Inc.
Calgary, Canada
A
11-50 Employees
-
Key takeaway
The company specializes in the end-to-end supply of nucleic acid products, including mRNA, which is directly relevant to RNA editing. Their focus on scalable GMP-grade manufacturing supports innovation in the field.
Reference
Service
SERVICES | Northern RNA
Ubigene Biosciences
New York, United States
B
51-100 Employees
-
Key takeaway
Ubigene is dedicated to enhancing gene editing through innovative technologies like their CRISPR-Uâ„¢, which significantly improves gene-editing efficiency. Their commitment to providing advanced gene-editing services and products positions them as a key player in the field of genome editing.
Reference
Service
| Ubigene
Technologies which have been searched by others and may be interesting for you:
RNA editing is a molecular process that alters the nucleotide sequence of RNA molecules after they have been transcribed from DNA. This modification can result in changes to the RNA sequence that can affect protein synthesis and function. In some cases, RNA editing leads to the generation of diverse protein variants from a single gene, contributing to the complexity of gene expression. The most common type of RNA editing involves the deamination of adenosine to inosine or cytidine to uridine, which can influence the stability, localization, and translation of RNA. This process is crucial for various biological functions, including neuronal function and immune responses, and is an area of active research for its potential implications in diseases and therapeutic applications.
RNA editing is a molecular process where specific nucleotides within an RNA molecule are modified after transcription. This alteration can change the coding potential of the RNA, leading to variations in gene expression and protein diversity. Enzymes such as adenosine deaminases act on RNA (ADARs) play a crucial role in this process by converting adenosine to inosine, which is interpreted as guanosine during translation. Such changes can influence the stability of the RNA, its localization within the cell, and the functionality of the proteins produced. RNA editing is vital for various biological functions, including the regulation of gene expression and the development of the nervous system. As a result, it has significant implications in health and disease, making it a key area of research in molecular biology and genetics.
RNA editing has several significant applications in medicine, particularly in the fields of gene therapy and precision medicine. One notable use is in the correction of genetic mutations that lead to diseases. By altering the RNA sequence, it is possible to produce functional proteins even when the underlying DNA contains errors. This approach holds promise for treating conditions such as muscular dystrophy and various neurodegenerative disorders. Additionally, RNA editing can enhance the efficacy of existing therapies. For example, it may be employed to improve the targeting of RNA-based drugs, ensuring they bind more effectively to their intended targets. This can potentially reduce side effects and improve patient outcomes. The ability to refine gene expression also opens avenues for developing personalized treatments tailored to an individual’s genetic makeup, contributing to more effective healthcare solutions.
RNA editing and gene editing are distinct processes that modify genetic information in different ways. RNA editing involves post-transcriptional modifications of RNA molecules, allowing for specific changes to be made to the RNA sequence after it has been transcribed from DNA. This can result in the production of different protein variants without altering the underlying DNA sequence. On the other hand, gene editing refers to techniques that make precise alterations to the DNA itself. Methods such as CRISPR-Cas9 enable researchers to add, delete, or replace segments of DNA, leading to permanent changes in the genome. While RNA editing is a reversible modification occurring at the RNA level, gene editing leads to lasting changes in the genetic material of an organism.
RNA editing presents several challenges that researchers and providers must navigate. One significant hurdle is the complexity of the editing process itself. Different types of RNA editing, such as adenosine-to-inosine (A-to-I) editing, require precise molecular mechanisms and enzymes, making it difficult to control and predict outcomes consistently. Another challenge involves the specificity of RNA editing. Off-target effects can occur, leading to unintended modifications that may disrupt normal cellular function or contribute to disease. Additionally, the delivery methods for editing tools, such as CRISPR systems or other molecular agents, are still being optimized. Achieving efficient and targeted delivery to specific tissues or cell types remains a key concern.
Some interesting numbers and facts about your company results for RNA Editing
| Country with most fitting companies | United States |
| Amount of fitting manufacturers | 7643 |
| Amount of suitable service providers | 8104 |
| Average amount of employees | 11-50 |
| Oldest suiting company | 1996 |
| Youngest suiting company | 2019 |
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Some interesting questions that has been asked about the results you have just received for RNA Editing
What are related technologies to RNA Editing?
Based on our calculations related technologies to RNA Editing are Biomedical (Red), Bioinformatics (Gold), Environmental Biotechnology (Grey), Agricultural Biotechnology (Green), Food Related Biotechnology (Yellow)
Which industries are mostly working on RNA Editing?
The most represented industries which are working in RNA Editing are IT, Software and Services, Other, Biotechnology, Healthcare, Marketing Services
How does ensun find these RNA Editing Companies?
ensun uses an advanced search and ranking system capable of sifting through millions of companies and hundreds of millions of products and services to identify suitable matches. This is achieved by leveraging cutting-edge technologies, including Artificial Intelligence.