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Lausanne, Switzerland
1-10 Employees
2020
All our products are linked by a common mission: to enable simple, fast and cost-efficient generation of "big RNA data" from diverse sample types. Daniel is the CTO and co-founder of Alithea since its incorporation in May 2020. Riccardo is the CEO and co-founder of Alithea Genomics since its incorporation in May 2020. Jan co-founded and served as director of Genohm, which was acquired by Agilent Technologies in 2018. Jan also served as Director and Chairman of Oystershell laboratories, a world-class developer of innovative consumer healthcare products. Roger is founder and CEO of Holonautic, a leader in the VR application development space. Since 2013, Deplancke is a group leader at the Swiss Institute of Bioinformatics. In 2011, Deplancke co-founded Genohm, a company delivering software (big data management) products and services for pharmaceutical and R&D laboratories, which was acquired by Agilent in May 2018.
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Featured
Alithea Genomics | Large-scale RNA sequencing
... Alithea Genomics offer large scale RNA sequencing - fast and cost-efficient generation of big RNA data from diverse sample types. ...
Warren, United States
11-50 Employees
2017
We develop tools that accelerate our client’s research and development process. We develop in silico solutions to reduce Avoidable Experimental Expenditure (AEE) and accelerate drug discovery and development stages for Small Molecules (SMOL) and biologics. Aganitha partners with global pharma to bring novel medicines to market faster. Aganitha is a new generation in silico company that integrates high-throughput sciences with deep learning-based generative models to solve complex drug discovery and development challenges. Offering services in computational sciences and technology to complement biopharma R&D. Scale up and augment R&D by working with extended teams/service providers while keeping costs low. Our AI models, guided by in-house experts, continuously improve on the increasingly available data to provide more intelligent solutions. Our focus on developing solutions for straight-through processing, high performance, robustness, scalability, extensibility, and automation helps biopharma R&D teams to minimize manual effort and accelerate drug discovery and development processes.
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Featured
RNA sequencing pipeline
... Learn more about our RNA sequencing ...
251-500 Employees
2004
At PacBio, our mission is to enable the promise of genomics to better human health. We know your vision can reveal the full potential of the genome, advance human health and the health of our planet. We are passionate about developing products that empower scientists to explore the full spectrum of genetic variation in any organism — from unraveling the mystery of rare diseases to improving the world’s food supply. PacBio Announces PureTarget™ Repeat Expansion Panel, Expanding its Portfolio of End-to-End Clinical Research Solutions March 12, 2024 | NASDAQ: PACB. PacBio to Present at Upcoming Investor Conferences February 26, 2024 | NASDAQ: PACB. PacBio Announces Fourth Quarter and Fiscal Year 2023 Financial Results February 15, 2024 | NASDAQ: PACB. Powered by PacBio: Selected publications from February 2024 March 08, 2024. And that is why your vision and pursuit are at the very center of what our company does — our product design, our customer support model, our partnerships, and even our identity.
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Featured
RNA sequencing
... RNA sequencing provides full-length transcripts to characterize the full diversity of transcriptomes and reliable isoform information. ...
La Rochelle, France
1-10 Employees
2017
At Labtoo, we give a lot of respect to the women and the men that thrive every day to change the world. We also diversified our services with biological specimen procurement. With solutions like we provide at Labtoo, we can save precious days, weeks, or even months before the new drug hit the market. The Labtoo method allows for finding solutions quickly at all stages of the R&D process and in any type of therapeutic area. The Labtoo method was developed around the outsourcing support for preclinical R&D: in vitro models, in vivo models, genomics, and proteomics services. This is the purpose of our work at Labtoo. Founded in 2017 by a team of scientists, Labtoo started as a digital marketplace. As scientists, we all know how dependent we are on the community, and how we need each other to move forward.
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Featured
Targeted RNA sequencing
... In the case where you already know which sequences you are looking for when sequencing a RNA sample, there might be a dedicated library preparation ...
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Featured
RNA Sequencing NGS Service
... NGS 次世代定序服務 RNA Sequencing - 威健股份有限公司 ...
Zurich, Switzerland
1-10 Employees
We are a team with specialized knowledge in computational methods, dedicated to providing high-quality bioinformatics solutions. We are committed to enhancing and optimizing bioinformatics solutions to meet the unique needs of each project, ensuring that our clients receive the most accurate and reliable results possible. Visit our services page to learn more about how we can provide valuable insights to optimize your project and drive your key decisions. Karda Genomics is a Swiss-based company providing bioinformatics services and delivering innovative solutions for companies seeking to leverage the power of sequencing technologies in their businesses. Our team comprises interdisciplinary experts who employ novel bioinformatics tools and proven analytical approaches to deliver reliable, high-quality results that businesses can trust. Joining forces with Karda Genomics means you can trust us to provide timely, accurate, and actionable results that enable you to optimize your projects and advance your market product. We offer life science organizations valuable insights into their data through trustworthy bioinformatic data analysis. Expertise in data analysis, machine learning and workflow development.
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Single cell RNA-sequencing (scRNA) – Karda Genomics
... Single cell RNA-sequencing (scRNA-seq) is revolutionizing our comprehension of essential biological processes like cell-related pathologies, immunity, and development. Advanced technology enables the high-resolution definition of the overall gene expression profiles of single cells, ...
Houston, United States
11-50 Employees
2011
Our mission is to assist our customers in advancing biological drug development. Our goal is to be the number one choice of vendors for high quality biologic assay services. Our leading scientists, in their careers, have successfully designed and executed several hundred studies under the strict GLP/GMP regulations of the US FDA, European and Japanese regulatory agencies. Avance Biosciences™ offers DNA sequencing, quantitative PCR (qPCR), and molecular biology services in compliance with the regulations of US FDA (cGMP/GLP), European, and Japanese regulatory agencies. We also provide non-regulated services, including next generation sequencing, to academic and industrial researchers. The Avance Biosciences™ team is committed to strict adherence to CGMP and GLP regulations enacted by the US, European, Japanese, and other international regulatory agencies. Our expertise in real-time PCR, digital droplet PCR (ddPCR), next-generation sequencing (NGS), and many other molecular biology, cell biology, and microbiology tools enable us to provide testing solutions that bolster our clients’ CGT programs. Avance Biosciences™ is a leading provider of biologics safety testing for both eukaryotic and prokaryotic development projects, offering Sanger sequencing, next generation DNA sequencing, real-time PCR, digital PCR, Southern blot, northern blot and other molecular biology and microbiology methods to support our clients’ biological drug development and manufacturing needs.
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Featured
DNA/RNA Sequencing
... DNA/RNA Sequencing - Avance ...
Aarhus, Denmark
1-10 Employees
2018
We deliver flexible solutions to your specific demands. We provide you with easy and accessible results that are interpretable and publication-ready. The duo quickly gained a reputation as the experts in NGS technology. This resulted in the two of them together founding omiics in 2018. NGS service provider with a focus on customer needs. We have spent many years building expertise in every detail of RNA sequencing - from laboratory design to tailoring the bioinformatic analysis - so that you can focus on the bigger picture, ensuring the success of your project. What sets us apart is that we deliver the highest quality at every step - from meticulous sample preparation to expert bioinformatics. We specialize in low input samples and have a large breadth of expertise.
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Featured
Services | omiics.com
... Standard products in RNA sequencing ...
Leuven, Belgium
11-50 Employees
We are a collaborative effort of the Centre of Human Genetics at KU Leuven and UZ Leuven for making state-of-the-art technologies, protocols and bioinformatic pipelines available for research and clinical diagnostics. We are a group of enthusiast lab scientists and bioinformaticians dedicated to enable next-generation sequencing and data analysis to everyone. The Genomics Core has multiple lllumina systems, provides access to single-cell sequencing technology and also to PacBio & Oxford Nanopore long-read technology. Our Operations Committee is a group of world-class leaders that leads the vision and push the boundaries on what the next step is in our future and provide their biomedical expertise in large-scale collaborative projects. Places are limited and are offered first-come, first-served. Coffee will be served and at lunch sandwiches will be offered. This event provides you with the opportunity to hear from your peers about their latest discoveries and how highly accurate long-read sequencing (HiFi sequencing) can help answer your toughest biological questions. The Sequel IIe System, now available at Genomics Core Leuven, delivers a comprehensive view of genomes, transcriptomes and epigenomes.
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RNA sequencing (RNA-seq) – Genomics Core Leuven
... RNA sequencing (RNA-seq) – Genomics Core ...
Utrecht, Netherlands
11-50 Employees
2018
We are focused on providing cutting-edge single-cell sequencing services to biopharmaceutical companies, health systems, and academic research centers globally. In alignment with our vision, we work on projects that help adapt single-cell applications to diagnostic and therapeutic purposes. We are the leading single-cell sequencing CRO providing high-impact insights to biopharmaceutical companies, health systems, and academic research centers globally. We are 100% focused on single-cell and spatial transcriptomics, enabling us to take on both large-scale projects and create customized solutions for each client project. We are committed to continuously integrating leading-edge technologies into our service offerings to ensure clients have access to the latest advancements. We are dedicated to maintaining a high-touch, collaborative relationship with clients as we scale our capacity to accommodate larger projects. What is now an industry-leading single-cell laboratory was once nothing more than a bold idea. The procedure was so laborious and the empty pipette boxes so numerous that Mauro committed himself to develop a higher-throughput, standardized protocol.
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Featured
Bulk RNA sequencing - Single Cell Discoveries
... Our bulk RNA sequencing service is of very high-quality, and able to process low-input samples, starting at 100 cells! Book a call today. ...
Technologies which have been searched by others and may be interesting for you:
Some interesting numbers and facts about the results you have just received for RNA Sequencing
| Country with most fitting companies | United States |
| Amount of fitting manufacturers | 60 |
| Amount of suitable service providers | 60 |
| Average amount of employees | 11-50 |
| Oldest suiting company | 2003 |
| Youngest suiting company | 2020 |
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RNA sequencing, often abbreviated as RNA-Seq, is a sophisticated molecular technique utilized for profiling the complete set of RNA transcripts within a cell or tissue at a given time. This method leverages the power of next-generation sequencing (NGS) technologies to provide a comprehensive view of the transcriptome, which includes coding and non-coding RNAs. By enabling the quantification of RNA levels and the identification of novel transcripts, RNA-Seq offers invaluable insights into the dynamic nature of gene expression across different conditions, developmental stages, or in response to treatments. This technique has revolutionized the field of genomics by facilitating a deeper understanding of complex regulatory networks that govern cellular functions. The impact of RNA sequencing extends across various domains, including molecular biology, genetics, and clinical research, where it aids in the discovery of disease-associated gene expressions, alternative splicing events, and mutations. Furthermore, RNA-Seq's precision in measuring transcript abundance and its sensitivity to detect rare and lowly expressed transcripts make it a critical tool for advancing personalized medicine, as it can uncover specific gene expression profiles linked to individual health conditions. Through these contributions, RNA sequencing continues to play a pivotal role in elucidating the molecular underpinnings of life and disease, driving forward the boundaries of scientific research and biomedical applications.
1. High Sensitivity and Specificity
RNA sequencing offers unparalleled sensitivity and specificity in detecting low-abundance transcripts. This allows researchers to identify and quantify rare RNA species that might be overlooked by other methods, providing a more comprehensive understanding of the transcriptome.
2. Dynamic Range
The technique boasts an extensive dynamic range, enabling the detection of both high and low expression genes within a single experiment. This is a significant advantage over array-based methods, which can struggle with quantifying transcripts at the extremes of abundance.
3. Flexibility and Scalability
RNA sequencing is highly adaptable, capable of analyzing a wide variety of RNA types, including mRNA, non-coding RNA, and microRNA. Additionally, it can be scaled to accommodate large-scale studies or focused, in-depth analysis of specific genes or pathways, making it versatile for both broad and targeted research applications.
4. Discovery of Novel Transcripts
Unlike methods that rely on pre-designed probes or primers, RNA sequencing can identify novel transcripts, splice variants, and fusion genes, offering insights into previously uncharacterized aspects of the genome. This capacity for discovery is critical for advancing our understanding of complex biological systems and diseases.
While evaluating the different suppliers make sure to check the following criteria:
1. Technology and Equipment
Ensure the supplier has the latest sequencing technology and well-maintained equipment, which are crucial for high-quality RNA sequencing results.
2. Experience and Expertise
Look for a supplier with a strong track record and expertise in RNA sequencing to ensure they can handle your specific project requirements efficiently.
3. Data Quality and Analysis
Assess their ability to provide comprehensive data analysis and quality control measures, which are essential for accurate interpretation of sequencing results.
4. Turnaround Time
Confirm the supplier can meet your project timelines, as delays can significantly impact research or diagnostic outcomes.
5. Cost-effectiveness
Compare pricing among suppliers to ensure you are getting competitive rates without compromising on the quality of the sequencing service.
6. Customer Support and Communication
Evaluate their customer service and communication channels. Reliable support is critical for addressing any concerns or modifications needed during the sequencing process.
In the pharmaceutical industry, RNA sequencing plays a crucial role in drug discovery and development. By analyzing the RNA profiles of diseased vs. healthy cells, researchers can identify potential drug targets and understand the mechanisms of action. This precision helps in developing more effective and targeted therapies, reducing the time and cost associated with drug development. In agriculture, RNA sequencing is used to improve crop traits and resistance to pests and diseases. By understanding the gene expression profiles of crops under different conditions, scientists can engineer plants that are more resilient to environmental stresses, enhancing food security and agricultural productivity. The healthcare sector leverages RNA sequencing for personalized medicine. By analyzing a patient's RNA, healthcare providers can predict disease risk, diagnose conditions more accurately, and tailor treatments to the individual's genetic makeup. This approach improves treatment outcomes and reduces the likelihood of adverse reactions, revolutionizing patient care. Environmental monitoring also benefits from RNA sequencing by assessing the health of ecosystems. Scientists can identify the presence and activity of different organisms in a sample, providing insights into biodiversity, pollution levels, and the impact of climate change. This information is vital for conservation efforts and policymaking, ensuring the sustainable management of natural resources.
RNA sequencing (RNA-seq) is a sophisticated technology that, as of my last knowledge update in 2023, has achieved a high Technology Readiness Level (TRL) of approximately 8 to 9. This assessment is based on its widespread adoption in research and clinical settings, demonstrating its maturity and reliability. The technology has undergone extensive development and validation, allowing for the comprehensive analysis of the transcriptome. This includes quantifying gene expression levels and identifying novel transcripts, splicing variants, and fusion genes. The high TRL is attributed to significant technical advancements, such as the development of high-throughput sequencing platforms and sophisticated bioinformatics tools for data analysis. These improvements have drastically increased the accuracy, speed, and affordability of RNA-seq, making it an indispensable tool in genetic research and personalized medicine. Furthermore, its application in diagnosing and understanding complex diseases like cancer, as well as in agricultural biotechnology, underscores its practical utility and effectiveness. The technical robustness and broad utility of RNA-seq underscore its high TRL, reflecting its readiness for application in a variety of settings without the need for further major development or validation.
In the Short-Term, advancements in RNA sequencing are expected to focus on enhancing precision and reducing costs. Emerging technologies are set to improve the accuracy of RNA sequencing, making it possible to detect and quantify even the most minute amounts of RNA in a sample. Additionally, efforts to streamline the sequencing process will likely result in more cost-effective solutions, making this technology accessible to a broader range of research and clinical labs. The Mid-Term development phase is anticipated to usher in significant improvements in the integration of artificial intelligence (AI) and machine learning (ML) with RNA sequencing technologies. These enhancements will facilitate the analysis of vast datasets, enabling researchers to uncover complex gene expression patterns and interactions at an unprecedented scale. This period will also see the development of more sophisticated multi-omics approaches, which will allow for the simultaneous analysis of RNA alongside DNA, proteins, and metabolites, providing a more comprehensive understanding of cellular processes. Looking towards the Long-Term, the horizon of RNA sequencing technology promises groundbreaking applications in personalized medicine and diagnostics. Innovations are expected to enable the real-time monitoring of gene expression levels in patients, paving the way for highly personalized therapeutic interventions. Furthermore, advancements in portable RNA sequencing devices could democratize the technology, allowing for on-site sequencing in diverse settings, from remote research facilities to point-of-care diagnostics in clinical environments.
Some interesting questions that has been asked about the results you have just received for RNA Sequencing
What are related technologies to RNA Sequencing?
Based on our calculations related technologies to RNA Sequencing are Biomedical (Red), Bioinformatics (Gold), Environmental Biotechnology (Grey), Agricultural Biotechnology (Green), Food Related Biotechnology (Yellow)
Who are Start-Ups in the field of RNA Sequencing?
Start-Ups who are working in RNA Sequencing are Alithea Genomics
Which industries are mostly working on RNA Sequencing?
The most represented industries which are working in RNA Sequencing are Biotechnology, Science and Engineering, Health Care, Professional Services, Data and Analytics
How does ensun find these RNA Sequencing Companies?
ensun uses an advanced search and ranking system capable of sifting through millions of companies and hundreds of millions of products and services to identify suitable matches. This is achieved by leveraging cutting-edge technologies, including Artificial Intelligence.
